(Q45057632)

English

Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-alpha induction of p38 and p42/p44 mitogen-activated protein kinases

scientific article published on 9 September 2004

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scholarly article

1 reference

Europe PubMed Central

9 December 2017

Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-alpha induction of p38 and p42/p44 mitogen-activated protein kinases (English)

1 reference

Europe PubMed Central

9 December 2017

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

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(RS)-rosiglitazone

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insulin resistance

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author name string

R Hernandez

1

1 reference

Europe PubMed Central

9 December 2017

T Teruel

2

1 reference

Europe PubMed Central

9 December 2017

C de Alvaro

3

1 reference

Europe PubMed Central

9 December 2017

M Lorenzo

4

1 reference

Europe PubMed Central

9 December 2017

publication date

9 September 2004

1 reference

Europe PubMed Central

9 December 2017

1 reference

Europe PubMed Central

9 December 2017

47

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Europe PubMed Central

9 December 2017

1615-1624

1 reference

Europe PubMed Central

9 December 2017

9

1 reference

Europe PubMed Central

9 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-004-1503-7

0 references

Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PLCgamma participates in insulin stimulation of glucose uptake through activation of PKCzeta in brown adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGF-I is a mitogen involved in differentiation-related gene expression in fetal rat brown adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A central role for JNK in obesity and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I and insulin induce adipogenic-related gene expression in fetal brown adipocyte primary cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of cell-permeable ceramides and tumor necrosis factor-alpha on insulin signaling and glucose uptake in 3T3-L1 adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A PPAR agonist improves TNF-alpha-induced insulin resistance of adipose tissue in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping of early signaling events in tumor necrosis factor-alpha -mediated lipolysis in human fat cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPARalpha activation by Wy 14643 induces transactivation of the rat UCP-1 promoter without increasing UCP-1 mRNA levels and attenuates PPARgamma-mediated increases in UCP-1 mRNA levels induced by rosiglitazone in fetal rat brown adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rosiglitazone produces insulin sensitisation by increasing expression of the insulin receptor and its tyrosine kinase activity in brown adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide mediates insulin resistance by tumor necrosis factor-alpha in brown adipocytes by maintaining Akt in an inactive dephosphorylated state

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Okadaic acid inhibits insulin-induced glucose transport in fetal brown adipocytes in an Akt-independent and protein kinase C zeta-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of TNF-alpha-induced insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38 mitogen-activated protein kinase mediates tumor necrosis factor-alpha-induced apoptosis in rat fetal brown adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rosiglitazone, an agonist of peroxisome-proliferator-activated receptor gamma (PPARgamma), decreases inhibitory serine phosphorylation of IRS1 in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor alpha inhibits signaling from the insulin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serine phosphorylation of insulin receptor substrate-1: a novel target for the reversal of insulin resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin/IGF-I rescues immortalized brown adipocytes from apoptosis down-regulating Bcl-xS expression, in a PI 3-kinase- and map kinase-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of PI 3-kinase and RAS blocks IGF-I and insulin-induced uncoupling protein 1 gene expression in brown adipocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms involved in tumor necrosis factor-alpha induction of insulin resistance and its reversal by thiazolidinedione(s).

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of tumor necrosis factor-alpha shows a strong relationship to insulin-stimulated glucose transport in human adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: potential role of p38 in the downregulation of GLUT4 expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance, defective insulin receptor substrate 2-associated phosphatidylinositol-3' kinase activation, and impaired atypical protein kinase C (zeta/lambda) activation in myotubes from obese patients with impaired glucose tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPAR gamma and the treatment of insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Troglitazone Antagonizes Tumor Necrosis Factor-α-induced Reprogramming of Adipocyte Gene Expression by Inhibiting the Transcriptional Regulatory Functions of NF-κB

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha acutely inhibits insulin signaling in human adipocytes: implication of the p80 tumor necrosis factor receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor alpha-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant p38 mitogen-activated protein kinase signalling in skeletal muscle from Type 2 diabetic patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rosiglitazone and retinoic acid induce uncoupling protein-1 (UCP-1) in a p38 mitogen-activated protein kinase-dependent manner in fetal primary brown adipocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha causes insulin receptor substrate-2-mediated insulin resistance and inhibits insulin-induced adipogenesis in fetal brown adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15365619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-004-1503-7

1 reference

Europe PubMed Central

9 December 2017

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0 references

1 reference

Europe PubMed Central

9 December 2017

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0 references

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