(Q45061834)

9 December 2017

title

The JAK3 inhibitor CP-690550 selectively reduces NK and CD8+ cell numbers in cynomolgus monkey blood following chronic oral dosing (English)

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9 December 2017

Maryrose Conklyn

1

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9 December 2017

Catharine Andresen

series ordinal

2

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9 December 2017

Paul Changelian

series ordinal

3

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9 December 2017

Elizabeth Kudlacz

series ordinal

4

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9 December 2017

publication date

15 September 2004

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Journal of Leukocyte Biology

9 December 2017

published in

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9 December 2017

volume

76

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9 December 2017

issue

6

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9 December 2017

page(s)

1248-1255

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Prevention of transplant rejection: current treatment guidelines and future developments

9 December 2017

cites work

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Cytokine receptor signaling pathways

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Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

21 January 2018

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Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

21 January 2018

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Defective expression of the interleukin-2/interleukin-15 receptor beta subunit leads to a natural killer cell-deficient form of severe combined immunodeficiency

21 January 2018

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Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

21 January 2018

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Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor

21 January 2018

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The novel JAK-3 inhibitor CP-690550 is a potent immunosuppressive agent in various murine models

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

21 January 2018

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Development and homeostasis of T cell memory in rhesus macaque

21 January 2018

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Consequences of restraint stress on natural killer cell activity, behavior, and hormone levels in rhesus macaques (Macaca mulatta).

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation

21 January 2018

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Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency

21 January 2018

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Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells.

21 January 2018

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IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro.

21 January 2018

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The pleiotropic functions of interleukin 15: not so interleukin 2-like after all.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.0504282

A potential role for interleukin-15 in the regulation of human natural killer cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

Turnover of naive- and memory-phenotype T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

IL-15 Promotes the Survival of Naive and Memory Phenotype CD8+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

Control of homeostasis of CD8+ memory T cells by opposing cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

IL-7 is critical for homeostatic proliferation and survival of naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

In remembrance of things past: memory T cells and transplant rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

The role of natural killer cells in transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

IL-15 is an essential mediator of peripheral NK-cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0504282

21 January 2018

Identifiers

DOI

10.1189/JLB.0504282

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9 December 2017

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