(Q45083256)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15454391%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells (English)

1 reference

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3 January 2020

1 reference

2

1 reference

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3 January 2020

author name string

Lucia Cilenti

1

1 reference

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3 January 2020

Mangala M Soundarapandian

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15454391%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Valerie Stratico

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15454391%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Adam Yerkes

5

1 reference

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3 January 2020

Kwon Moo Park

6

1 reference

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3 January 2020

Alice M Sheridan

7

1 reference

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3 January 2020

Emad S Alnemri

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15454391%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Joseph V Bonventre

9

1 reference

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3 January 2020

Antonis S Zervos

10

1 reference

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3 January 2020

publication date

28 September 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15454391%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Renal Physiology

3 January 2020

published in

1 reference

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3 January 2020

volume

288

1 reference

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3 January 2020

issue

2

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3 January 2020

page(s)

F371-9

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The HtrA1 serine protease is down-regulated during human melanoma progression and represses growth of metastatic melanoma cells

3 January 2020

cites work

1 reference

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Intramitochondrial serine protease activity of Omi/HtrA2 is required for caspase-independent cell death of human neutrophils

21 January 2018

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grim, a novel cell death gene in Drosophila

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Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2.

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Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death

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The HtrA Family of Proteases

21 January 2018

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Cisplatin-induced renal cell apoptosis: caspase 3-dependent and -independent pathways

21 January 2018

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Three-color flow cytometric assay for the study of the mechanisms of cell-mediated cytotoxicity.

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Mxi2, a splice variant of p38 stress-activated kinase, is a distal nephron protein regulated with kidney ischemia

21 January 2018

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Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia

21 January 2018

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F16, a mitochondriotoxic compound, triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell

21 January 2018

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Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

21 January 2018

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The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity

21 January 2018

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Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

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A rapid single-laser flow cytometric method for discrimination of early apoptotic cells in a heterogenous cell population.

21 January 2018

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Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage

21 January 2018

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CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals.

21 January 2018

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Random mutagenesis of PDZOmi domain and selection of mutants that specifically bind the Myc proto-oncogene and induce apoptosis

21 January 2018

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Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells

21 January 2018

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The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border

21 January 2018

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Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine

21 January 2018

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Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi

21 January 2018

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Role of Omi/HtrA2 in apoptotic cell death after myocardial ischemia and reperfusion

21 January 2018

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The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

21 January 2018

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Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and HtrA2

21 January 2018

1 reference

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Cisplatin and nifedipine: synergistic cytotoxicity against murine solid tumors and their metastases.

21 January 2018

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Cell death induced by acute renal injury: a perspective on the contributions of apoptosis and necrosis

21 January 2018

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The HtrA family of serine proteases

21 January 2018

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Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction.

21 January 2018

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Schedule-dependent synergism of edatrexate and cisplatin in combination in the A549 lung-cancer cell line as assessed by median-effect analysis

21 January 2018

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HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney

21 January 2018

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Apoptosis versus necrosis during cold storage and rewarming of human renal proximal tubular cells

21 January 2018

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Cell biology and molecular mechanisms of injury in ischemic acute renal failure

21 January 2018

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A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein.

21 January 2018

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Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2

21 January 2018

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A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

21 January 2018

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

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Renal ischemia-reperfusion injury in the rat is prevented by a novel immune modulation therapy

21 January 2018

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Apoptotic mechanisms in acute renal failure

21 January 2018

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Tubular cell damage in acute renal failure-apoptosis, necrosis, or both

21 January 2018

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The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

21 January 2018

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HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

21 January 2018

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Inhibition of reaper-induced apoptosis by interaction with inhibitor of apoptosis proteins (IAPs).

21 January 2018

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Inhibitor of apoptosis proteins physically interact with and block apoptosis induced by Drosophila proteins HID and GRIM.

21 January 2018

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21 January 2018

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Possible involvement of oxidative stress in cisplatin-induced apoptosis in LLC-PK1 cells

21 January 2018

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Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis

21 January 2018

1 reference

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Primary structure of a putative serine protease specific for IGF-binding proteins

21 January 2018

1 reference

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