(Q45092709)

9 December 2017

Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells (English)

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9 December 2017

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Matthew C Lorincz

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9 December 2017

David R Dickerson

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2

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9 December 2017

Mike Schmitt

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3

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9 December 2017

Mark Groudine

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4

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9 December 2017

3 October 2004

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Nature Structural & Molecular Biology

9 December 2017

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9 December 2017

11

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9 December 2017

1068-1075

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9 December 2017

11

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https://scigraph.springernature.com/pub.10.1038/nsmb840

9 December 2017

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cites work

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Molecular archeology of L1 insertions in the human genome.

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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DNA methylation models histone acetylation

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Methylation-mediated proviral silencing is associated with MeCP2 recruitment and localized histone H3 deacetylation

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Specific protection of methylated CpGs in mammalian nuclei

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Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene

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Genomic targeting of methylated DNA: influence of methylation on transcription, replication, chromatin structure, and histone acetylation

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Stability of patch methylation and its impact in regions of transcriptional initiation and elongation

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Effect of regional DNA methylation on gene expression

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DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa.

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Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal.

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Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation

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The endothelin receptor B (EDNRB) promoter displays heterogeneous, site specific methylation patterns in normal and tumor cells

21 January 2018

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Promoter-proximal pausing of RNA polymerase II defines a general rate-limiting step after transcription initiation

21 January 2018

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Histone H3 lysine 4 methylation patterns in higher eukaryotic genes

21 January 2018

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The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote

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Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs.

21 January 2018

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Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

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Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity

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Histone methylation: dynamic or static?

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Gene silencing: trans-histone regulatory pathway in chromatin

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Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation

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Transcriptional inhibition of genes with severe histone h3 hypoacetylation in the coding region

21 January 2018

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Effects of histone tail domains on the rate of transcriptional elongation through a nucleosome

21 January 2018

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Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA.

21 January 2018

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A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome.

21 January 2018

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Creation of genomic methylation patterns

21 January 2018

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The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes

21 January 2018

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Alu repeat analysis in the complete human genome: trends and variations with respect to genomic composition.

21 January 2018

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Dynamic analysis of proviral induction and De Novo methylation: implications for a histone deacetylase-independent, methylation density-dependent mechanism of transcriptional repression

21 January 2018

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Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

21 January 2018

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The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation

21 January 2018

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Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation

21 January 2018

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A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

21 January 2018

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MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

31 March 2020

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Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange

31 March 2020

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A positive role for histone acetylation in transcription factor access to nucleosomal DNA

31 March 2020

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Effects of histone acetylation on the solubility and folding of the chromatin fiber

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSMB840

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Dimensions Publication ID

9 December 2017

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