(Q45094647)

English

A dileucine motif and a cluster of acidic amino acids in the second cytoplasmic domain of the batten disease-related CLN3 protein are required for efficient lysosomal targeting

scientific article published on 5 October 2004

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scholarly article

1 reference

Europe PubMed Central

9 December 2017

A dileucine motif and a cluster of acidic amino acids in the second cytoplasmic domain of the batten disease-related CLN3 protein are required for efficient lysosomal targeting (English)

1 reference

Europe PubMed Central

9 December 2017

author name string

Stephan Storch

1

1 reference

Europe PubMed Central

9 December 2017

Sandra Pohl

2

1 reference

Europe PubMed Central

9 December 2017

Thomas Braulke

3

1 reference

Europe PubMed Central

9 December 2017

language of work or name

0 references

publication date

5 October 2004

1 reference

Europe PubMed Central

9 December 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

9 December 2017

279

1 reference

Europe PubMed Central

9 December 2017

53625-53634

1 reference

Europe PubMed Central

9 December 2017

51

1 reference

Europe PubMed Central

9 December 2017

Isolation of a novel gene underlying batten disease, CLN3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Membrane topology of CLN3, the protein underlying Batten disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Characterization of Cln3p, the gene product responsible for juvenile neuronal ceroid lipofuscinosis, as a lysosomal integral membrane glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Two motifs target Batten disease protein CLN3 to lysosomes in transfected nonneuronal and neuronal cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Biosynthesis and intracellular targeting of the CLN3 protein defective in Batten disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

CLN3 protein is targeted to neuronal synapses but excluded from synaptic vesicles: new clues to Batten disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Intracellular trafficking of CLN3, the protein underlying the childhood neurodegenerative disease, Batten disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Action of BTN1, the yeast orthologue of the gene mutated in Batten disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

CLN3 protein regulates lysosomal pH and alters intracellular processing of Alzheimer's amyloid-beta protein precursor and cathepsin D in human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Motifs within the CLN3 protein: modulation of cell growth rates and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

A role in vacuolar arginine transport for yeast Btn1p and for human CLN3, the protein defective in Batten disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Rapid analytical and preparative isolation of functional endosomes by free flow electrophoresis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

At the acidic edge: emerging functions for lysosomal membrane proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Signals for sorting of transmembrane proteins to endosomes and lysosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Adaptor-related proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

The mammalian AP-3 adaptor-like complex mediates the intracellular transport of lysosomal membrane glycoproteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Specificity of interaction between adaptor-complex medium chains and the tyrosine-based sorting motifs of TGN38 and lgp120

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

A region from the medium chain adaptor subunit (mu) recognizes leucine- and tyrosine-based sorting signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Medium chains of adaptor complexes AP-1 and AP-2 recognize leucine-based sorting signals from the invariant chain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

The leucine-based sorting motifs in the cytoplasmic domain of the invariant chain are recognized by the clathrin adaptors AP1 and AP2 and their medium chains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Subunit H of the V-ATPase involved in endocytosis shows homology to beta-adaptins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

The GGA proteins: adaptors on the move

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Multiple C-terminal motifs of the 46-kDa mannose 6-phosphate receptor tail contribute to efficient binding of medium chains of AP-2 and AP-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Serine phosphorylation site of the 46-kDa mannose 6-phosphate receptor is required for transport to the plasma membrane in Madin-Darby canine kidney and mouse fibroblast cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Differences in the endosomal distributions of the two mannose 6-phosphate receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Cysteine34 of the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor is reversibly palmitoylated and required for normal trafficking and lysosomal enzyme sorting

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Proper sorting of the cation-dependent mannose 6-phosphate receptor in endosomes depends on a pair of aromatic amino acids in its cytoplasmic tail

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

AP-3 mediates tyrosinase but not TRP-1 trafficking in human melanocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Cross-species homology of the CLN3 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

A di-leucine sequence and a cluster of acidic amino acids are required for dynamic retention in the endosomal recycling compartment of fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

A model for Batten disease protein CLN3: functional implications from homology and mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Analysis of intracellular distribution and trafficking of the CLN3 protein in fusion with the green fluorescent protein in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Structural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

The Dileucine Motif Within the Tail of MPR46 is Required for Sorting of the Receptor in Endosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410930200

21 January 2018

Identifiers

10.1074/JBC.M410930200

1 reference

Europe PubMed Central

9 December 2017

1 reference

Europe PubMed Central

9 December 2017

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