(Q45117927)

English

Metabolism and disposition of the HIV-1 protease inhibitor lopinavir (ABT-378) given in combination with ritonavir in rats, dogs, and humans

scientific article published in September 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Metabolism and disposition of the HIV-1 protease inhibitor lopinavir (ABT-378) given in combination with ritonavir in rats, dogs, and humans (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Gondi N Kumar

1

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Venkata K Jayanti

2

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Marianne K Johnson

3

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

John Uchic

4

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Samuel Thomas

5

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Ronald D Lee

6

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Brian A Grabowski

7

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Hing L Sham

8

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Dale J Kempf

9

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Jon F Denissen

10

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Kennan C Marsh

11

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Eugene Sun

12

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Stanley A Roberts

13

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

publication date

1 September 2004

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

21

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

1622-1630

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interaction between ritonavir and indinavir in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and disposition of the HIV-1 protease inhibitor ritonavir (ABT-538) in rats, dogs, and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rational design of peptide-based HIV proteinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FDA approves new protease inhibitor for HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent inhibition of the cytochrome P-450 3A-mediated human liver microsomal metabolism of a novel HIV protease inhibitor by ritonavir: A positive drug-drug interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interactions between two human immunodeficiency virus protease inhibitors, ritonavir and saquinavir

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ordered accumulation of mutations in HIV protease confers resistance to ritonavir

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human serum attenuates the activity of protease inhibitors toward wild-type and mutant human immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease. European-Australian Collaborative Ritonavir Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro effect of alpha1-acid glycoprotein on the anti-human immunodeficiency virus (HIV) activity of the protease inhibitor CGP 61755: a comparative study with other relevant HIV protease inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro metabolism of the HIV-1 protease inhibitor ABT-378: species comparison and metabolite identification

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and antiviral activities of the major metabolites of the HIV protease inhibitor ABT-378 (Lopinavir).

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic and intestinal metabolism of indinavir, an HIV protease inhibitor, in rat and human microsomes. Major role of CYP3A

1 reference

https://pubmed.ncbi.nlm.nih.gov/15497688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/B:PHAM.0000041457.64638.8D

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

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