(Q45124244)

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Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain.

scientific article published on 25 October 2004

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4 January 2020

Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain (English)

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4 January 2020

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Christophe C Marchal

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Jason Molitoris

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Nancy Pech

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Jason Towe

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Simon J Atkinson

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Mary C Dinauer

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25 October 2004

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Journal of Biological Chemistry

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953-964

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4 January 2020

Regulation of neutrophil function by Rac GTPases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Rho GTPases in cell biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Characterization of RAC3, a novel member of the Rho family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Comparative functional analysis of the Rac GTPases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Structural requirements for PAK activation by Rac GTPases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Rac2 is an essential regulator of neutrophil nicotinamide adenine dinucleotide phosphate oxidase activation in response to specific signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Respiratory burst in human neutrophils

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Long-term high-level reconstitution of NADPH oxidase activity in murine X-linked chronic granulomatous disease using a bicistronic vector expressing gp91phox and a Delta LNGFR cell surface marker

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

The C-terminal domain of Rac1 contains two motifs that control targeting and signaling specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Isotype-specific degradation of Rac activated by the cytotoxic necrotizing factor 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

The formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response element

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Ras proteins: different signals from different locations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Human monocytes use Rac1, not Rac2, in the NADPH oxidase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Molecular basis for Rac2 regulation of phagocyte NADPH oxidase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Regulation of NADPH oxidase activity by Rac GTPase activating protein(s).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Eukaryotic chemotaxis: distinctions between directional sensing and polarization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408820200

21 January 2018

Identifiers

10.1074/JBC.M408820200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15504745%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15504745%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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