(Q45130172)

English

Susceptibility of cerebellar granule neurons from GM2/GD2 synthase-null mice to apoptosis induced by glutamate excitotoxicity and elevated KCl: rescue by GM1 and LIGA20.

scientific article published in January 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Susceptibility of cerebellar granule neurons from GM2/GD2 synthase-null mice to apoptosis induced by glutamate excitotoxicity and elevated KCl: rescue by GM1 and LIGA20. (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

1 reference

based on heuristic

inferred from title

author name string

Gusheng Wu

1

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Zi-Hua Lu

2

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Xin Xie

3

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Robert W Ledeen

4

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

publication date

1 January 2004

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Europe PubMed Central

PubMed publication ID

9 December 2017

number of pages

9

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based on heuristic

inferred from page(s)

Glycoconjugate Journal

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Europe PubMed Central

PubMed publication ID

9 December 2017

21

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Europe PubMed Central

PubMed publication ID

9 December 2017

6

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Europe PubMed Central

PubMed publication ID

9 December 2017

305-313

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganglioside derivative LIGA20 reduces NMDA neurotoxicity in neonatal rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental appearance of nuclear GM1 in neurons of the central and peripheral nervous systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cell death: the calcium-apoptosis link

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic model of substrate deprivation therapy for a glycosphingolipid storage disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gangliosides activate Trk receptors by inducing the release of neurotrophins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of a sodium-calcium exchanger in the nuclear envelope by nuclear GM1 ganglioside

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganglioside function in calcium homeostasis and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LIGA20, a lyso derivative of ganglioside GM1, given orally after cortical thrombosis reduces infarct size and associated cognition deficit

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular parameters of semisynthetic derivatives of gangliosides and sphingosine in monolayers at the air-water interface

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional role for complex gangliosides: motor deficits in GM2/GD2 synthase knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C6 cells express a sodium-calcium exchanger/GM1 complex in the nuclear envelope but have no exchanger in the plasma membrane: comparison to astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amyloid beta peptide abeta (25-35) induces apoptosis independent of p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trophic effect of cholera toxin B subunit in cultured cerebellar granule neurons: modulation of intracellular calcium by GM1 ganglioside

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of nuclear gangliosides in rat brain: concentration, composition, and developmental changes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain content of glycosphingolipids after oral administration of monosialogangliosides GM1 and LIGA20 to rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear calcium signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of caspase-3 and apoptosis in cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate-induced neuronal death in primary cultures of cerebellar granule cells: protection by synthetic derivatives of endogenous sphingolipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The semisynthetic glycosphingolipid LIGA20 potently protects neurons against apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gangliosides normalize distorted single-cell intracellular free Ca2+ dynamics after toxic doses of glutamate in cerebellar granule cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism for ganglioside-mediated modulation of a calmodulin-dependent enzyme. Modulation of calmodulin-dependent cyclic nucleotide phosphodiesterase activity through binding of gangliosides to calmodulin and the enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The calcium pump of the liver nuclear membrane is identical to that of endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of nuclear GM1 accompanies axon-like, but not dendrite-like, outgrowth in NG108-15 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agents that promote protein phosphorylation inhibit the activity of the Na+/Ca2+ exchanger and prolong Ca2+ transients in bovine chromaffin cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive and negative controls by protein kinases of sodium-dependent Ca2+ efflux from cultured bovine adrenal chromaffin cells stimulated by lysophosphatidic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional calcium accumulation and kainic acid (KA)-induced limbic seizure status in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebellar neurons lacking complex gangliosides degenerate in the presence of depolarizing levels of potassium

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of ganglioside biosynthesis in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induced and spontaneous neuritogenesis are associated with enhanced expression of ganglioside GM1 in the nuclear membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP-dependent accumulation and inositol trisphosphate- or cyclic ADP-ribose-mediated release of Ca2+ from the nuclear envelope

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of neuro-2a cells against calcium ionophore cytotoxicity by gangliosides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of N-methyl-D-aspartate receptor-mediated increases in cytosolic calcium in cultured rat cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate neurotoxicity and diseases of the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of calcium-dependent excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nucleus is insulated from large cytosolic calcium ion changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gangliosides as modulators of neuronal calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GM1 Ganglioside in the Nuclear Membrane Modulates Nuclear Calcium Homeostasis During Neurite Outgrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of cortical neuronal apoptosis by gangliosides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant NG108-15 cells (NG-CR72) deficient in GM1 synthase respond aberrantly to axonogenic stimuli and are vulnerable to calcium-induced apoptosis: they are rescued with LIGA-20.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of ganglioside profiles in nuclei and whole cells of NG108-15 and NG-CR72 lines: changes in response to different neuritogenic stimuli

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current evidence suggests independent regulation of nuclear calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear lipids: key signaling effectors in the nervous system and other tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection by gangliosides against glutamate excitotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing roles of synaptic and extrasynaptic NMDA receptors in neuronal calcium signalling and BDNF gene regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and isotype analysis of protein kinase C from rat liver nuclei.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orally administered glycolipid derivative LIGA20 reduces infarct volume and behavioral impairment after focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-amyloid peptide-induced death of PC 12 cells and cerebellar granule cell neurons is inhibited by long-term lithium treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA and glycine regulate the affinity of the Mg2+-block site in NR1-1a/NR2A NMDA receptor channels expressed in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of ganglioside biosynthesis in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15514479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/B:GLYC.0000046273.68493.F7

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

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