(Q45153419)

10 December 2017

Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication (English)

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10 December 2017

Gerald W Hsu

1

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10 December 2017

Xuanwei Huang

2

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10 December 2017

Natalia P Luneva

3

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10 December 2017

Nicholas E Geacintov

4

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10 December 2017

Lorena S Beese

5

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10 December 2017

language of work or name

English

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publication date

16 November 2004

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Journal of Biological Chemistry

10 December 2017

7

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based on heuristic

inferred from page(s)

published in

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10 December 2017

280

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10 December 2017

3764-3770

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10 December 2017

5

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Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

10 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Differences in mutagenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Mutagenic selectivity at the HPRT locus in V-79 cells: comparison of mutations caused by bay-region benzo[a]pyrene 7,8-diol-9,-10-epoxide enantiomers with high and low carcinogenic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase zeta in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

DNA polymerase action on benzo[a]pyrene-DNA adducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Effects of benzo[a]pyrene DNA adducts on Escherichia coli DNA polymerase I (Klenow fragment) primer-template interactions: evidence for inhibition of the catalytically active ternary complex formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Effects of benzo[a]pyrene adduct stereochemistry on downstream DNA replication in vitro: evidence for different adduct conformations within the active site of DNA polymerase I (Klenow fragment).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

An open and closed case for all polymerases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Function and structure relationships in DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

DNA polymerases: structural diversity and common mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Multi-stage proofreading in DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Mechanism of DNA replication fidelity for three mutants of DNA polymerase I: Klenow fragment KF(exo+), KF(polA5), and KF(exo-).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Biochemical basis of DNA replication fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Conformational coupling in DNA polymerase fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

21 January 2018

DNA replication fidelity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Structures of mismatch replication errors observed in a DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Active site tightness and substrate fit in DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Spectroscopic characteristics and site I/site II classification of cis and trans benzo[a]pyrene diolepoxide enantiomer-guanosine adducts in oligonucleotides and polynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Role of hydrophobic effects in the reaction of a polynuclear aromatic diol epoxide with oligodeoxynucleotides in aqueous solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

NMR solution structures of stereoisometric covalent polycyclic aromatic carcinogen-DNA adduct: principles, patterns, and diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Crystal structure of a thermostable Bacillus DNA polymerase I large fragment at 2.1 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

PRODRG, a program for generating molecular topologies and unique molecular descriptors from coordinates of small molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Visualizing and quantifying molecular goodness-of-fit: small-probe contact dots with explicit hydrogen atoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

3DNA: a software package for the analysis, rebuilding and visualization of three-dimensional nucleic acid structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Toward understanding the mutagenicity of an environmental carcinogen: structural insights into nucleotide incorporation preferences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function relationship through experimental and computational approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Error-prone lesion bypass by human DNA polymerase eta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Replication of a cis-syn thymine dimer at atomic resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411276200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411276200

1 reference

release_t3hfkgze75h3rpbv7tyflr27ve

10 December 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/t3hfkgze75h3rpbv7tyflr27ve

mapped directly with Wikidata item

24 November 2022

based on heuristic

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