(Q45171116)

10 December 2017

title

A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3. (English)

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10 December 2017

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D D Hu

1

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10 December 2017

C A White

2

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10 December 2017

S Panzer-Knodle

3

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10 December 2017

J D Page

4

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10 December 2017

N Nicholson

5

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10 December 2017

J W Smith

6

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10 December 2017

language of work or name

English

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publication date

1 February 1999

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Journal of Biological Chemistry

10 December 2017

published in

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10 December 2017

volume

274

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10 December 2017

issue

8

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10 December 2017

page(s)

4633-4639

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GPIIb-IIIa: the responsive integrin

10 December 2017

cites work

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21 January 2018

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Integrins: versatility, modulation, and signaling in cell adhesion

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Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity

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Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

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Integrin cytoplasmic domains mediate inside-out signal transduction

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Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

21 January 2018

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Signal transduction by the platelet integrin alpha IIb beta 3: induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells

21 January 2018

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Signal transduction from the extracellular matrix

21 January 2018

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Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins

21 January 2018

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Activation of distinct alpha5beta1-mediated signaling pathways by fibronectin's cell adhesion and matrix assembly domains

21 January 2018

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Cell adhesion in vascular biology. New insights into integrin-ligand interaction

21 January 2018

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The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets

21 January 2018

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Inhibition of platelet function with synthetic peptides designed to be high-affinity antagonists of fibrinogen binding to platelets

21 January 2018

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Platelets have more than one binding site for von Willebrand factor

21 January 2018

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Role of fibrinogen alpha and gamma chain sites in platelet aggregation

21 January 2018

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An allosteric Ca2+ binding site on the beta3-integrins that regulates the dissociation rate for RGD ligands

21 January 2018

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Arginine-glycine-aspartic acid adhesion receptors

21 January 2018

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Determination of kinetic constants for the interaction between a monoclonal antibody and peptides using surface plasmon resonance

21 January 2018

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Rapid and simple platelet function assay to assess glycoprotein IIb/IIIa receptor blockade.

21 January 2018

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High-affinity self-reactive human antibodies by design and selection: targeting the integrin ligand binding site

21 January 2018

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The biologic and clinical spectrum of Glanzmann's thrombasthenia: implications of integrin alpha IIb beta 3 for its pathogenesis

21 January 2018

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A new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg----214Trp mutation

21 January 2018

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Platelet GPIIb/IIIa antagonists: the first anti-integrin receptor therapeutics

21 January 2018

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Dual regulation of ligand binding by CD11b I domain. Inhibition of intercellular adhesion and monocyte procoagulant activity by a factor X-derived peptide

21 January 2018

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Networking in the hemostatic system. Integrin alphaiibbeta3 binds prothrombin and influences its activation

21 January 2018

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Recognition site for the platelet receptor is present on the 15-residue carboxy-terminal fragment of the γ chain of human fibrinogen and is not involved in the fibrin polymerization reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.4633

Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.4633

Characterization of Binding of an RGD Mimetic, [(3)H]-SC-52012, to Platelet GPIIb/IIIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.4633

21 January 2018

Identifiers

DOI

10.1074/JBC.274.8.4633

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10 December 2017

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