(Q45234525)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22057094%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

The human relevant potency threshold: reducing uncertainty by human calibration of cumulative risk assessments (English)

1 reference

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16 January 2020

5

1 reference

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16 January 2020

author name string

C J Borgert

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22057094%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

E V Sargent

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22057094%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

G Casella

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22057094%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

D R Dietrich

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22057094%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

R J Golden

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22057094%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

28 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22057094%20AND%20SRC:MED&resulttype=core&format=json

Regulatory Toxicology and Pharmacology

16 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22057094%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

62

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22057094%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22057094%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

313-328

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22057094%20AND%20SRC:MED&resulttype=core&format=json

Toxicogenomic difference between diethylstilbestrol and 17beta-estradiol in mouse testicular gene expression by neonatal exposure

16 January 2020

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Acute effects of polychlorinated biphenyl-containing and -free transformer fluids on rat testicular steroidogenesis

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Inhibition of rat testicular androgenesis by a polychlorinated biphenyl mixture aroclor 1248

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Testosterone-stimulated weanlings as an alternative to castrated male rats in the Hershberger anti-androgen assay

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Rapid decline of persistent organochlorine pollutants in serum among young Swedish males.

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Nonlinear statistical models for the joint action of toxins.

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Dihydrotestosterone and the concept of 5alpha-reductase inhibition in human benign prostatic hyperplasia

7 January 2021

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Hazard to the developing male reproductive system from cumulative exposure to phthalate esters--dibutyl phthalate, diisobutyl phthalate, butylbenzyl phthalate, diethylhexyl phthalate, dipentyl phthalate, and diisononyl phthalate

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Synergism, antagonism, or additivity of dietary supplements: application of theory to case studies

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Effects of in utero exposure to finasteride on androgen-dependent reproductive development in the male rat.

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Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat.

7 January 2021

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Synergistic disruption of external male sex organ development by a mixture of four antiandrogens

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Rodent Leydig cell tumorigenesis: a review of the physiology, pathology, mechanisms, and relevance to humans

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Estrogen receptor-alpha mediates the detrimental effects of neonatal diethylstilbestrol (DES) exposure in the murine reproductive tract

7 January 2021

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Proposed mode of action for in utero effects of some phthalate esters on the developing male reproductive tract

7 January 2021

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Courage for simplification and imperfection in the 21st century assessment of "Endocrine disruption".

7 January 2021

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Human exposure to endocrine-disrupting chemicals and prenatal risk factors for cryptorchidism and hypospadias: a nested case-control study

7 January 2021

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Mode of action: impaired fetal leydig cell function--effects on male reproductive development produced by certain phthalate esters

7 January 2021

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Fetal mouse phthalate exposure shows that Gonocyte multinucleation is not associated with decreased testicular testosterone

7 January 2021

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Environmental endocrine modulators and human health: an assessment of the biological evidence

7 January 2021

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Effects of finasteride (MK-906), a 5 alpha-reductase inhibitor, on circulating androgens in male volunteers

7 January 2021

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Diethylstilbestrol-treated adult rats with altered epididymal sperm numbers and sperm motility parameters, but without alterations in sperm production and sperm morphology

7 January 2021

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Abnormal morphology of the penis in male rats exposed neonatally to diethylstilbestrol is associated with altered profile of estrogen receptor-alpha protein, but not of androgen receptor protein: a developmental and immunocytochemical study

7 January 2021

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Estrogen-induced developmental disorders of the rat penis involve both estrogen receptor (ESR)- and androgen receptor (AR)-mediated pathways

7 January 2021

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Exposure to TCDD during development permanently alters reproductive function in male Long Evans rats and hamsters: reduced ejaculated and epididymal sperm numbers and sex accessory gland weights in offspring with normal androgenic status.

7 January 2021

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A dose-response analysis of the reproductive effects of a single gestational dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male Long Evans Hooded rat offspring

7 January 2021

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Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual di

7 January 2021

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Diethylstilbestrol inhibits the expression of the steroidogenic acute regulatory protein in mouse fetal testis

7 January 2021

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Prenatal testosterone and luteinizing hormone levels in male rats exposed during pregnancy to 2,3,7,8-tetrachlorodibenzo-p-dioxin and diethylstilbestrol

7 January 2021

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Effects of 4-tert-octylphenol, 4-tert-butylphenol, and diethylstilbestrol on prenatal testosterone surge in the rat.

7 January 2021

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Effects of monobutyl and di(n-butyl) phthalate in vitro on steroidogenesis and Leydig cell aggregation in fetal testis explants from the rat: comparison with effects in vivo in the fetal rat and neonatal marmoset and in vitro in the human

7 January 2021

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Combined exposure to anti-androgens exacerbates disruption of sexual differentiation in the rat.

7 January 2021

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A mixture of the "antiandrogens" linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashion

7 January 2021

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Historical changes in serum PCB and DDT levels in an environmentally-exposed cohort

7 January 2021

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Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genes

7 January 2021

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Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats

7 January 2021

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A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner

7 January 2021

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7 January 2021

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Species-specific dibutyl phthalate fetal testis endocrine disruption correlates with inhibition of SREBP2-dependent gene expression pathways

7 January 2021

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Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist

7 January 2021

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7 January 2021

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Effects of neonatal administration of diethylstilbestrol in male hamsters: disruption of reproductive function in adults after apparently normal pubertal development.

7 January 2021

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Combined exposures to anti-androgenic chemicals: steps towards cumulative risk assessment

7 January 2021

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Toxic interactions among environmental pollutants: corroborating laboratory observations with human experience

7 January 2021

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Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat.

7 January 2021

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Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production.

7 January 2021

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Simple designs and model-free tests for synergy.

7 January 2021

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Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture

7 January 2021

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7 January 2021

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Evaluation of the male pubertal onset assay to detect testosterone and steroid biosynthesis inhibitors in CD rats

7 January 2021

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Mal-development of the penis and loss of fertility in male rats treated neonatally with female contraceptive 17alpha-ethinyl estradiol: a dose-response study and a comparative study with a known estrogenic teratogen diethylstilbestrol

7 January 2021

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Dysgenesis and histological changes of genitals and perturbations of gene expression in male rats after in utero exposure to antiandrogen mixtures.

7 January 2021

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Effects of neonatal exposure to 4-tert-octylphenol, diethylstilbestrol, and flutamide on steroidogenesis in infantile rat testis

7 January 2021

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The OECD program to validate the rat Hershberger bioassay to screen compounds for in vivo androgen and antiandrogen responses: phase 2 dose-response studies

7 January 2021

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A mixture of seven antiandrogens induces reproductive malformations in rats

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach

7 January 2021

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Steroidogenesis in the fetal testis and its susceptibility to disruption by exogenous compounds

7 January 2021

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The 'oestrogen hypothesis'- where do we stand now?

7 January 2021

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Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects

7 January 2021

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Dose-dependent transitions in mechanisms of toxicity

7 January 2021

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Clinical pharmacokinetics and pharmacodynamics of finasteride

7 January 2021

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An overview of drug combination analysis with isobolograms

7 January 2021

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Interactions between drugs and occupied receptors

7 January 2021

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What is new in cryptorchidism and hypospadias--a critical review on the testicular dysgenesis hypothesis

7 January 2021

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Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): environmental connection

7 January 2021

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Direct effects of diethylstilbestrol on the gene expression of the cholesterol side-chain cleavage enzyme (P450scc) in testicular Leydig cells

7 January 2021

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Chemoprevention strategies for prostate cancer: The role of 5α-reductase inhibitors

7 January 2021

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