(Q45247890)

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Nuclear receptor peroxisome proliferator-activated receptor-gamma is activated in rat microglial cells by the anti-inflammatory drug HCT1026, a derivative of flurbiprofen

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Europe PubMed Central

11 December 2017

Nuclear receptor peroxisome proliferator-activated receptor-gamma is activated in rat microglial cells by the anti-inflammatory drug HCT1026, a derivative of flurbiprofen (English)

1 reference

Europe PubMed Central

11 December 2017

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Antonietta Bernardo

1

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Europe PubMed Central

11 December 2017

Maria Antonietta Ajmone-Cat

2

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Europe PubMed Central

11 December 2017

Laura Gasparini

3

1 reference

Europe PubMed Central

11 December 2017

Ennio Ongini

4

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Europe PubMed Central

11 December 2017

Luisa Minghetti

5

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Europe PubMed Central

11 December 2017

language of work or name

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publication date

1 February 2005

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Europe PubMed Central

11 December 2017

Journal of Neurochemistry

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Europe PubMed Central

11 December 2017

92

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Europe PubMed Central

11 December 2017

4

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Europe PubMed Central

11 December 2017

895-903

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Europe PubMed Central

11 December 2017

Differential effects of the nonsteroidal antiinflammatory drug flurbiprofen and its nitric oxide-releasing derivative, nitroflurbiprofen, on prostaglandin E(2), interleukin-1beta, and nitric oxide synthesis by activated microglia.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Metabolic profile of NO-flurbiprofen (HCT1026) in rat brain and plasma: a LC-MS study.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Stereoselective disposition of ibuprofen enantiomers in human cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

15-deoxy-delta12,14-prostaglandin J2 regulates the functional state and the survival of microglial cells through multiple molecular mechanisms.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxy-Delta(12,14)-prostaglandin J(2) in activated murine macrophages

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis

1 reference

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21 January 2018

Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study

1 reference

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21 January 2018

A nitric oxide releasing derivative of flurbiprofen inhibits experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Peripheral administration of novel anti-inflammatories can attenuate the effects of chronic inflammation within the CNS.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Opposite effects of flurbiprofen and the nitroxybutyl ester of flurbiprofen on apoptosis in cultured guinea-pig gastric mucous cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Pharmacology and potential therapeutic applications of nitric oxide-releasing non-steroidal anti-inflammatory and related nitric oxide-donating drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Selective inhibition of Abeta42 production by NSAID R-enantiomers

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Natural ligands of PPARgamma: are prostaglandin J(2) derivatives really playing the part?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Glitazones differentially regulate primary astrocyte and glioma cell survival. Involvement of reactive oxygen species and peroxisome proliferator-activated receptor-gamma.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

NO-flurbiprofen attenuates excitotoxin-induced brain inflammation, and releases nitric oxide in the brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

The influence of brain inflammation upon neuronal adenosine A2B receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

The non-cyclooxygenase targets of non-steroidal anti-inflammatory drugs, lipoxygenases, peroxisome proliferator-activated receptor, inhibitor of kappa B kinase, and NF kappa B, do not reduce amyloid beta 42 production

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Anti-inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Nitration of PPARgamma inhibits ligand-dependent translocation into the nucleus in a macrophage-like cell line, RAW 264

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

Peroxisome proliferator-activated receptor gamma and metabolic disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2004.02932.X

21 January 2018

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10.1111/J.1471-4159.2004.02932.X

1 reference

Europe PubMed Central

11 December 2017

1 reference

Europe PubMed Central

11 December 2017

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