(Q45248068)

English

The carriage of risk variants of CDKAL1 impairs beta-cell function in both diabetic and non-diabetic patients and reduces response to non-sulfonylurea and sulfonylurea agonists of the pancreatic KATP channel

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Europe PubMed Central

PubMed publication ID

11 December 2017

The carriage of risk variants of CDKAL1 impairs beta-cell function in both diabetic and non-diabetic patients and reduces response to non-sulfonylurea and sulfonylurea agonists of the pancreatic KATP channel (English)

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Europe PubMed Central

PubMed publication ID

11 December 2017

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author name string

Dimitry A Chistiakov

1

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

V A Potapov

2

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

S A Smetanina

3

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

L N Bel'chikova

4

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

L A Suplotova

5

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Europe PubMed Central

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11 December 2017

V V Nosikov

6

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Europe PubMed Central

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11 December 2017

publication date

25 May 2011

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Europe PubMed Central

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11 December 2017

Acta Diabetologica

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Europe PubMed Central

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11 December 2017

48

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Europe PubMed Central

PubMed publication ID

11 December 2017

3

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Europe PubMed Central

PubMed publication ID

11 December 2017

227-235

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Europe PubMed Central

PubMed publication ID

11 December 2017

https://scigraph.springernature.com/pub.10.1007/s00592-011-0299-4

0 references

Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: where are the insulin resistance genes?

1 reference

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21 January 2018

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

1 reference

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21 January 2018

A brain-specific activator of cyclin-dependent kinase 5.

1 reference

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Extraneuronal roles of cyclin-dependent kinase 5.

1 reference

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21 January 2018

Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells

1 reference

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21 January 2018

Cdk5-dependent regulation of glucose-stimulated insulin secretion.

1 reference

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21 January 2018

Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity

1 reference

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21 January 2018

Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion.

1 reference

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21 January 2018

The risk allele load accelerates the age-dependent decline in beta cell function

1 reference

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21 January 2018

Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.

1 reference

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21 January 2018

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function

1 reference

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21 January 2018

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

1 reference

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21 January 2018

Analysis of novel risk loci for type 2 diabetes in a general French population: the D.E.S.I.R. study

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps

1 reference

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21 January 2018

Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population.

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Positive association between variations in CDKAL1 and type 2 diabetes in Han Chinese individuals

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Genetic variations in the pancreatic ATP-sensitive potassium channel, beta-cell dysfunction, and susceptibility to type 2 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

2LD, GENECOUNTING and HAP: Computer programs for linkage disequilibrium analysis

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Type 2 diabetes risk alleles are associated with reduced size at birth

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene.

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Impaired beta cell glucose sensitivity and whole-body insulin sensitivity as predictors of hyperglycaemia in non-diabetic subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis

1 reference

https://api.crossref.org/works/10.1007%2FS00592-011-0299-4

21 January 2018

ABCC8 and ABCC9: ABC transporters that regulate K+ channels

1 reference

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The role of the Cdk5-p35 kinase in neuronal development

1 reference

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Replication of association between polymorphisms of the pancreatic ATP-sensitive potassium channel and susceptibility to type 2 diabetes in two Russian urban populations

1 reference

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21 January 2018

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10.1007/S00592-011-0299-4

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

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