(Q45272355)

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Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats

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scholarly article

1 reference

Europe PubMed Central

11 December 2017

Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats (English)

1 reference

Europe PubMed Central

11 December 2017

4

1 reference

Europe PubMed Central

11 December 2017

author name string

Khemraj Hirani

1

1 reference

Europe PubMed Central

11 December 2017

Ajay N Sharma

2

1 reference

Europe PubMed Central

11 December 2017

Nishant S Jain

3

1 reference

Europe PubMed Central

11 December 2017

Chandrabhan T Chopde

5

1 reference

Europe PubMed Central

11 December 2017

publication date

18 February 2005

1 reference

Europe PubMed Central

11 December 2017

Psychopharmacology

1 reference

Europe PubMed Central

11 December 2017

180

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Europe PubMed Central

11 December 2017

2

1 reference

Europe PubMed Central

11 December 2017

267-278

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Europe PubMed Central

11 December 2017

https://scigraph.springernature.com/pub.10.1007/s00213-005-2169-7

0 references

Alcohol dependence and anxiety disorders: what is the relationship?

1 reference

https://api.crossref.org/works/10.1007%2FS00213-005-2169-7

21 January 2018

GABAergic neurosteroid modulation of ethanol actions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of alcohol on eating behavior: influence of mood and perceived intoxication

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurosteroids and GABAA receptor function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From ion currents to genomic analysis: recent advances in GABAA receptor research.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral action of ethanol in Porsolt's forced swim test: modulation by 3 alpha-hydroxy-5 alpha-pregnan-20-one

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracranial metyrapone stimulates CRF-ACTH axis in the teleost, Clarias batrachus: possible role of neurosteroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alcohol and neurotransmitter interactions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol specifically potentiates GABA-mediated neurotransmission in feline cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alcohols and neurotransmitter gated ion channels: past, present and future

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reinforcing effects of ethanol are altered by the endogenous neurosteroid, allopregnanolone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dehydroepiandrosterone and dehydroepiandrosterone sulfate as neuroactive neurosteroids.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neural substrates for the motor-activating properties of psychostimulants: a review of recent findings.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo injection of antisense oligodeoxynucleotides to G alpha subunits and supraspinal analgesia evoked by mu and delta opioid agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prior maze experience required to alter midazolam effects in rats submitted to the elevated plus-maze.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral benzodiazepine binding sites: Effect of PK 11195, 1-(2-chlorophenyl)-n-methyl-n-(1-methylpropyl)-3-isoquinolinecarboxamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol-induced increases in neuroactive steroids in the rat brain and plasma are absent in adrenalectomized and gonadectomized rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute alcohol administration stimulates the activity of hypothalamic neurons that express corticotropin-releasing factor and vasopressin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An update on GABAA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Foulds' "general instability" and "psychopathy" 16PF scales and their relationship to psychiatric mood state

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5α-dihydroprogesterone in psychiatric disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of neuroactive steroid allopregnanolone in antipsychotic-like action of olanzapine in rodents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of chronic ethanol consumption and withdrawal on the neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one in male and female rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of a plus-maze to measure anxiety in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Neurosteroids: behavioral aspects and physiological implications]

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAergic agents prevent alpha-melanocyte stimulating hormone induced anxiety and anorexia in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone enhances ethanol-induced modulation of mesocortical dopamine neurons: antagonism by finasteride.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen receptor immunoreactivity in the adult primate brain: neuronal distribution and association with p75, trkA, and choline acetyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rewarding effect of the neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of naloxone and D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 and the protein kinase inhibitors H7 and H8 on acute morphine dependence and antinociceptive tolerance in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol and neurosteroid interactions in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal analog of alcohol dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiety in mice following acute aspartame and ethanol exposure.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroactive steroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol potentiates gamma-aminobutyric acid-mediated inhibition in the inferior colliculus: evidence for local ethanol/gamma-aminobutyric acid interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of progesterone or neuroactive steroid?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course of ethanol's effects on locomotor activity, exploration and anxiety in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute ethanol administration and acute allopregnanolone administration impair spatial memory in the Morris water task

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurosteroid consumption has anxiolytic effects in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic effect of progesterone is associated with increases in cortical allopregnanolone and GABAA receptor function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behaviorally selective effects of neuroactive steroids on plus-maze anxiety in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol-GABAA receptor interactions: a comparison between cell lines and cerebellar Purkinje cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of peripheral mitochondrial benzodiazepine receptors in the hippocampus stimulates allopregnanolone synthesis and produces anxiolytic-like effects in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative behavioral characterization of the neuroactive steroids 3α-OH,5α-pregnan-20-one and 3α-OH,5β-pregnan-20-one in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific and nonspecific effects of ethanol vapor on plasma corticosterone in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of gamma-aminobutyric acid (GABA) receptors and the feeding response by neurosteroids in Hydra vulgaris

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that 3α-hydroxy-5α-pregnan-20-one is a physiologically relevant modulator of gaba-ergic neurotransmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of voluntary ethanol and saccharin consumption by the neurosteroid allopregnanolone in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between the effects of metyrapone treatment on depressed mood and urinary steroid profiles

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroactive steroid modulation of GABAA receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chlordiazepoxide attenuates response suppression induced by corticotropin-releasing factor in the conflict test

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of serotonin with ethanol: clinical and animal studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAergic influences on plus-maze behaviour in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of stress in alcohol use, alcoholism treatment, and relapse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol potentiates GABA- and glycine-induced chloride currents in chick spinal cord neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that the anxiolytic-like effects of chlordiazepoxide on the elevated plus maze are confounded by increases in locomotor activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The estrus cycle, sensitivity to convulsants and the anticonvulsant effect of a neuroactive steroid

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Permissive role of brain allopregnanolone content in the regulation of pentobarbital-induced righting reflex loss.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catecholamine depletion by reserpine blocks the anxiolytic actions of ethanol in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mCPP-induced anxiety in the light-dark box in rats--a new method for screening anxiolytic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further pharmacological validation of the BALB/c neophobia in the free exploratory paradigm as an animal model of trait anxiety.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression by gamma-hydroxybutyric acid of ethanol withdrawal syndrome in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol markedly increases "GABAergic" neurosteroids in alcohol-preferring rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one modulates ethanol-induced loss of righting reflex in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroactive steroid concentrations following metyrapone administration in depressed patients and healthy volunteers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The clinical potentials of endogenous neurosteroids.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone receptor-mediated effects of neuroactive steroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroactive steroid modulators of the stress response

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time-dependent changes in rat brain neuroactive steroid concentrations and GABAA receptor function after acute stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurosteroid 3 alpha-hydroxy-5 alpha-pregnan-20-one affects dopamine-mediated behavior in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An essential component in steroid synthesis, the steroidogenic acute regulatory protein, is expressed in discrete regions of the brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroidogenesis in rat brain induced by short- and long-term administration of carbamazepine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discussions arising from: Cloninger, CR. A. unified biosocial theory of personality and its role in the development of anxiety states

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Precursors of the neurosteroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/15719223

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00213-005-2169-7

1 reference

Europe PubMed Central

11 December 2017

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1 reference

Europe PubMed Central

11 December 2017

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