(Q45303314)

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Adenoviral astrocyte-specific expression of BDNF in the striata of mice transgenic for Huntington's disease delays the onset of the motor phenotype

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Europe PubMed Central

PubMed publication ID

11 December 2017

Adenoviral astrocyte-specific expression of BDNF in the striata of mice transgenic for Huntington's disease delays the onset of the motor phenotype (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

Huntington's disease

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1 reference

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author name string

Leticia Arregui

1

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

Jorge A Benítez

2

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

Luis F Razgado

3

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

Paula Vergara

4

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

Jose Segovia

5

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

publication date

17 June 2011

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Europe PubMed Central

PubMed publication ID

11 December 2017

Cellular and Molecular Neurobiology

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Europe PubMed Central

PubMed publication ID

11 December 2017

31

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Europe PubMed Central

PubMed publication ID

11 December 2017

8

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Europe PubMed Central

PubMed publication ID

11 December 2017

1229-1243

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

High potassium enhances secretion of neurotrophic factors from cultured astrocytes

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Anterograde transport of brain-derived neurotrophic factor and its role in the brain

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Gene therapy targeting in the central nervous system

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Targeted-simultaneous expression of Gas1 and p53 using a bicistronic adenoviral vector in gliomas

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Neurotrophins and their receptors: a convergence point for many signalling pathways

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

A small-molecule therapeutic lead for Huntington's disease: preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Akt is altered in an animal model of Huntington's disease and in patients

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Increased cell proliferation and neurogenesis in the adult human Huntington's disease brain

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Sustained striatal ciliary neurotrophic factor expression negatively affects behavior and gene expression in normal and R6/1 mice

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Brain-derived neurotrophic factor in Huntington disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Brain-derived neurotrophic factor signaling does not stimulate subventricular zone neurogenesis in adult mice and rats

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Biochemical and histochemical analysis of 71 kDa dystrophin isoform (Dp71f) in rat brain

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Brain-derived neurotrophic factor over-expression in the forebrain ameliorates Huntington's disease phenotypes in mice

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

A simplified system for generating recombinant adenoviruses

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Early behavioral deficits in R6/2 mice suitable for use in preclinical drug testing

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Standardization and statistical approaches to therapeutic trials in the R6/2 mouse

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

AAV-mediated gene delivery of BDNF or GDNF is neuroprotective in a model of Huntington disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Therapeutic potential of neurotrophic factors in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

AKT-sensitive or insensitive pathways of toxicity in glial cells and neurons in Drosophila models of Huntington's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNS

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

The detection and measurement of locomotor deficits in a transgenic mouse model of Huntington's disease are task- and protocol-dependent: influence of non-motor factors on locomotor function

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Striatal oxidative damage parallels the expression of a neurological phenotype in mice transgenic for the mutation of Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Basal ganglia mechanisms underlying precision grip force control

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Differential loss of striatal projection neurons in Huntington disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Differentiation-dependent expression of transgenes in engineered astrocyte cell lines

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Huntington's disease: Changes in striatal proteins reflect astrocytic gliosis

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Astrocytes: biology and pathology

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Gene therapy in a rodent model of Parkinson's disease using differentiated C6 cells expressing a GFAP-tyrosine hydroxylase transgene

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Astrocytic expression of transgene in the rat brain mediated by baculovirus vectors containing an astrocyte-specific promoter

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

BDNF overexpression in the forebrain rescues Huntington's disease phenotypes in YAC128 mice

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Role of brain-derived neurotrophic factor in Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS10571-011-9725-Y

21 January 2018

Cyclic AMP decreases the expression of a neuronal marker (GAD67) and increases the expression of an astroglial marker (GFAP) in C6 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21681558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the striatal DARPP-32/ARPP-21 phenotype in GABAergic neurons requires neurotrophins in vivo and in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21681558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological classification of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21681558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary astrocytes retrovirally transduced with a tyrosine hydroxylase transgene driven by a glial-specific promoter elicit behavioral recovery in experimental parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21681558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/21681558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GFAP promoter directs astrocyte-specific expression in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21681558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of BDNF and NT-3 but not PDGF against hypoglycemic injury to cultured striatal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/21681558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10571-011-9725-Y

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

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