(Q45304348)

11 December 2017

CREB-binding protein modulates repeat instability in a Drosophila model for polyQ disease (English)

1 reference

11 December 2017

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Joonil Jung

1

1 reference

PubMed ID

17332375

11 December 2017

Nancy Bonini

series ordinal

2

1 reference

PubMed ID

17332375

11 December 2017

language of work or name

English

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publication date

1 March 2007

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11 December 2017

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11 December 2017

315

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11 December 2017

1857-1859

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11 December 2017

5820

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Repeat instability: mechanisms of dynamic mutations

11 December 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

A SCA7 CAG/CTG repeat expansion is stable in Drosophila melanogaster despite modulation of genomic context and gene dosage

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Tissue-specific somatic mosaicism in spinal and bulbar muscular atrophy is dependent on CAG-repeat length and androgen receptor--gene expression level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Age and insertion site dependence of repeat number instability of a human DM1 transgene in individual mouse sperm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Increased trinucleotide repeat instability with advanced maternal age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Advances in mechanisms of genetic instability related to hereditary neurological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

CTG repeat instability and size variation timing in DNA repair-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Transcription promotes contraction of CAG repeat tracts in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Histone acetyl transferases: a role in DNA repair and DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Aberrant histone acetylation, altered transcription, and retinal degeneration in a Drosophila model of polyglutamine disease are rescued by CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Altered protein acetylation in polyglutamine diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

RNA-mediated neurodegeneration caused by the fragile X premutation rCGG repeats in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Neurodegeneration. Huntington's research points to possible new therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

Study of three intragenic polymorphisms in the Machado-Joseph disease gene (MJD1) in relation to genetic instability of the (CAG)n tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1139517

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1139517

1 reference

11 December 2017

1 reference

PubMed ID

17332375