(Q45314268)

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Fanconi Anemia Pathway

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-6783310)

Fanconi anaemia pathway
FA pathway

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8 July 2022

interstrand cross-link repair

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8 July 2022

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13 July 2022

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8 July 2022

10.1016/J.CUB.2017.07.043

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https://identifiers.org/reactome:R-HSA-6783310

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8 July 2022

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8 July 2022

FANCM:FAAP24 and APITD1:STRA13 bind ICL-DNA

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8 July 2022

FA core complex assembles at DNA interstrand crosslinks (ICLs)

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8 July 2022

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8 July 2022

FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex

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8 July 2022

Monoubiquitination of FANCD2:FANCI

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8 July 2022

The complex of ATR and ATRIP is recruited to ICL-DNA

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8 July 2022

ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA

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8 July 2022

FANCD2 deubiquitination by USP1:WDR48

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8 July 2022

DNA nucleases bind monoubiquitinated ID2 complex

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8 July 2022

DNA nucleases unhook the interstrand crosslink (ICL)

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8 July 2022

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8 July 2022

Translesion synthesis across unhooked ICL by POLN

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8 July 2022

Drug-induced formation of DNA interstrand crosslinks

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8 July 2022

Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

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8 July 2022

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

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8 July 2022

A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway

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8 July 2022

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

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8 July 2022

Deciphering the BRCA1 Tumor Suppressor Network

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8 July 2022

DNA interstrand crosslink repair and cancer

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8 July 2022

Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways.

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8 July 2022

PALB2 mutations and breast-cancer risk

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q45314268)

Fanconi Anemia Pathway

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