(Q50287477)

English

ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-6788392)

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8 July 2022

Fanconi Anemia Pathway

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-6788392

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FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm]

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8 July 2022

ATR:ATRIP [nucleoplasm]

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8 July 2022

p-FANCD2:p-FANCI:UBE2T:p-FA Core Complex:ICL-DNA [nucleoplasm]

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8 July 2022

p-RPA heterotrimer [nucleoplasm]

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8 July 2022

FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm]

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8 July 2022

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

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8 July 2022

The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response

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8 July 2022

ATR-ATRIP kinase complex triggers activation of the Fanconi anemia DNA repair pathway

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8 July 2022

A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair

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8 July 2022

Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance

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8 July 2022

ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions.

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q50287477)

ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA

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