(Q45318264)

English

WNT5A-dependent internalization of FZD4

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5099900)

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Statements

biological pathway

1 reference

8 July 2022

1 reference

13 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5099900

1 reference

8 July 2022

WNT5A binds FZD4

1 reference

8 July 2022

WNT5A-FZD4 recruits DVL2

1 reference

8 July 2022

DVL2 is phosphorylated by PKC

1 reference

8 July 2022

p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis

1 reference

8 July 2022

WNT5A:FZD4 is endocytosed

1 reference

8 July 2022

Structural Analysis of the Interaction between Dishevelled2 and Clathrin AP-2 Adaptor, A Critical Step in Noncanonical Wnt Signaling

1 reference

8 July 2022

Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling

1 reference

8 July 2022

Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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