(Q50298832)

English

WNT5A:FZD4 is endocytosed

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5138459)

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Statements

biological process

1 reference

8 July 2022

WNT5A-dependent internalization of FZD4

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5138459

1 reference

8 July 2022

WNT5A:FZD4:p-DVL2:ARRB2:AP-2:clathrin [plasma membrane]

1

value of statement has role

1 reference

8 July 2022

Arrestin beta 2

1

value of statement has role

1 reference

8 July 2022

WNT5A:FZD4:p-DVL2:AP-2:clathrin [clathrin-coated endocytic vesicle membrane]

1

value of statement has role

1 reference

8 July 2022

Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling

1 reference

8 July 2022

Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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