(Q45340366)

English

Evaluation of the effects of food on the single-dose pharmacokinetics of trametinib, a first-in-class MEK inhibitor, in patients with cancer

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Evaluation of the effects of food on the single-dose pharmacokinetics of trametinib, a first-in-class MEK inhibitor, in patients with cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

1 reference

ChEBI release 2020-05-28

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Donna S Cox

1

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Kyri Papadopoulos

2

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Lei Fang

3

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

John Bauman

4

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Patricia LoRusso

5

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Anthony Tolcher

6

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Amita Patnaik

7

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Carolyn Pendry

8

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Keith Orford

9

1 reference

Europe PubMed Central

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13 December 2017

Daniele Ouellet

10

1 reference

Europe PubMed Central

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13 December 2017

publication date

25 July 2013

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Europe PubMed Central

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13 December 2017

The Journal of Clinical Pharmacology

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Europe PubMed Central

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13 December 2017

53

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

946-954

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

The "SWOT" of BRAF inhibition in melanoma: RAF inhibitors, MEK inhibitors or both?

1 reference

https://api.crossref.org/works/10.1002%2FJCPH.115

21 January 2018

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

1 reference

https://api.crossref.org/works/10.1002%2FJCPH.115

21 January 2018

(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

1 reference

https://api.crossref.org/works/10.1002%2FJCPH.115

21 January 2018

Comprehensive predictive biomarker analysis for MEK inhibitor GSK1120212.

1 reference

https://api.crossref.org/works/10.1002%2FJCPH.115

21 January 2018

GSK1120212 (JTP-74057) is an inhibitor of MEK activity and activation with favorable pharmacokinetic properties for sustained in vivo pathway inhibition

1 reference

https://api.crossref.org/works/10.1002%2FJCPH.115

21 January 2018

Discovery of a Highly Potent and Selective MEK Inhibitor: GSK1120212 (JTP-74057 DMSO Solvate).

1 reference

https://api.crossref.org/works/10.1002%2FJCPH.115

21 January 2018

Safety, pharmacokinetic, pharmacodynamic, and efficacy data for the oral MEK inhibitor trametinib: a phase 1 dose-escalation trial

1 reference

https://api.crossref.org/works/10.1002%2FJCPH.115

21 January 2018

Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial

1 reference

https://api.crossref.org/works/10.1002%2FJCPH.115

21 January 2018

Improved survival with MEK inhibition in BRAF-mutated melanoma

1 reference

https://api.crossref.org/works/10.1002%2FJCPH.115

21 January 2018

Estimation of oral bioavailability of a long half-life drug in healthy subjects

1 reference

https://api.crossref.org/works/10.1002%2FJCPH.115

21 January 2018

Identifiers

10.1002/JCPH.115

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

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