(Q45345920)

13 December 2017

Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1. (English)

1 reference

13 December 2017

Kei Miyano

1

1 reference

13 December 2017

Noriko Ueno

series ordinal

2

1 reference

13 December 2017

Ryu Takeya

series ordinal

3

1 reference

13 December 2017

Hideki Sumimoto

series ordinal

4

1 reference

13 December 2017

language of work or name

English

0 references

publication date

8 June 2006

1 reference

Journal of Biological Chemistry

13 December 2017

1 reference

13 December 2017

281

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13 December 2017

31

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13 December 2017

21857-21868

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NADPH oxidases: not just for leukocytes anymore!

13 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

NOX enzymes and the biology of reactive oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

The Nox family of NAD(P)H oxidases: host defense and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

GTPases and reactive oxygen species: switches for killing and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Molecular composition and regulation of the Nox family NAD(P)H oxidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Structure and regulation of the neutrophil respiratory burst oxidase: comparison with nonphagocyte oxidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Assembly of the phagocyte NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Activation and assembly of the NADPH oxidase: a structural perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Electron transfer in the superoxide-generating NADPH oxidase complex reconstituted in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Simultaneous presence of p47(phox) and flavocytochrome b-245 are required for the activation of NADPH oxidase by anionic amphiphiles. Evidence for an intermediate state of oxidase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Molecular basis for Rac2 regulation of phagocyte NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Dual role of Rac in the assembly of NADPH oxidase, tethering to the membrane and activation of p67phox: a study based on mutagenesis of p67phox-Rac1 chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Binding of FAD to cytochrome b558 is facilitated during activation of the phagocyte NADPH oxidase, leading to superoxide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phox

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Interactions between the cytosolic components p47phox and p67phox of the human neutrophil NADPH oxidase that are not required for activation in the cell-free system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Mapping of functional domains in p47(phox) involved in the activation of NADPH oxidase by "peptide walking".

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

A region C-terminal to the proline-rich core of p47phox regulates activation of the phagocyte NADPH oxidase by interacting with the C-terminal SH3 domain of p67phox

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Structure of the TPR domain of p67phox in complex with Rac.GTP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Mutagenesis of p22(phox) histidine 94. A histidine in this position is not required for flavocytochrome b558 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

A fusion protein between rac and p67phox (1-210) reconstitutes NADPH oxidase with higher activity and stability than the individual components

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Roles for proline-rich regions of p47phox and p67phox in the phagocyte NADPH oxidase activation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Regulation of the neutrophil respiratory burst oxidase. Identification of an activation domain in p67(phox).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Activation of the superoxide-generating NADPH oxidase by chimeric proteins consisting of segments of the cytosolic component p67(phox) and the small GTPase Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

A prenylated p67phox-Rac1 chimera elicits NADPH-dependent superoxide production by phagocyte membranes in the absence of an activator and of p47phox: conversion of a pagan NADPH oxidase to monotheism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Cell transformation by the superoxide-generating oxidase Mox1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

A mammalian H+ channel generated through alternative splicing of the NADPH oxidase homolog NOH-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

NAD(P)H oxidase 1, a product of differentiated colon epithelial cells, can partially replace glycoprotein 91phox in the regulated production of superoxide by phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Novel Human Homologues of p47 and p67 Participate in Activation of Superoxide-producing NADPH Oxidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Functional association of nox1 with p22phox in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Two novel proteins activate superoxide generation by the NADPH oxidase NOX1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Rac regulates cardiovascular superoxide through diverse molecular interactions: more than a binary GTP switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Regulation of H2O2 generation in thyroid cells does not involve Rac1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Helicobacter pylori lipopolysaccharide activates Rac1 and transcription of NADPH oxidase Nox1 and its organizer NOXO1 in guinea pig gastric mucosal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Identification of two human Rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

pEF-BOS, a powerful mammalian expression vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Guanine nucleotides induce tyrosine phosphorylation and activation of the respiratory burst in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Mechanism of activation of Pak1 kinase by membrane localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Activation of Rac and Cdc42 by integrins mediates cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Nox3 regulation by NOXO1, p47phox, and p67phox.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

Nox1-dependent reactive oxygen generation is regulated by Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

NADPH oxidase activity is independent of p47phox in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513665200

21 January 2018

Identifiers

DOI

10.1074/JBC.M513665200

1 reference

13 December 2017

1 reference