(Q45377444)

English

Efficacy and safety of the p38 MAPK inhibitor losmapimod for patients with chronic obstructive pulmonary disease: a randomised, double-blind, placebo-controlled trial

scientific article published on 5 December 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Efficacy and safety of the p38 MAPK inhibitor losmapimod for patients with chronic obstructive pulmonary disease: a randomised, double-blind, placebo-controlled trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

0 references

chronic obstructive pulmonary disease

1 reference

based on heuristic

inferred from title

author name string

Henrik Watz

1

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Helen Barnacle

2

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Benjamin F Hartley

3

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Robert Chan

4

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

publication date

5 December 2013

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

The Lancet. Respiratory medicine

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

63-72

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Raised CRP levels mark metabolic and functional impairment in advanced COPD.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Systemic inflammation in chronic obstructive pulmonary disease: a population-based study

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Extrapulmonary effects of chronic obstructive pulmonary disease on physical activity: a cross-sectional study.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Physical activity and clinical and functional status in COPD.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Plasma markers of inflammation and incidence of hospitalisations for COPD: results from a population-based cohort study

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Inflammatory Biomarkers Improve Clinical Prediction of Mortality in Chronic Obstructive Pulmonary Disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic obstructive pulmonary disease and comorbidities

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of p38 mitogen-activated protein kinase inhibition on vascular and systemic inflammation in patients with atherosclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

New therapeutic targets in cardiology: p38 alpha mitogen-activated protein kinase for ischemic heart disease.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The p38 mitogen-activated protein kinase pathway--a potential target for intervention in infarction, hypertrophy, and heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased activation of p38 MAPK in COPD

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased phosphorylated p38 mitogen-activated protein kinase in COPD lungs.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

MAPK signaling in the quadriceps of patients with chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Synergistic effects of p38 mitogen-activated protein kinase inhibition with a corticosteroid in alveolar macrophages from patients with chronic obstructive pulmonary disease.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p38 mitogen-activated protein kinase pathways in asthma and COPD.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

P38 inhibition in COPD; cautious optimism

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

An oral inhibitor of p38 MAP kinase reduces plasma fibrinogen in patients with chronic obstructive pulmonary disease.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Physical activity monitoring in COPD: compliance and associations with clinical characteristics in a multicenter study

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Physical activity in patients with COPD.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Standardisation of spirometry

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Development and Validation of an Improved, COPD-Specific Version of the St. George Respiratory Questionnaire.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Development and first validation of the COPD Assessment Test.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Updating the minimal important difference for six-minute walk distance in patients with chronic obstructive pulmonary disease.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The minimal important difference of exercise tests in severe COPD.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Reproducibility of 6-minute walking test in patients with COPD.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Physiological effects of roflumilast at rest and during exercise in COPD

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Bronchodilator reversibility in chronic obstructive pulmonary disease: use and limitations

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy and safety of the oral p38 inhibitor PH-797804 in chronic obstructive pulmonary disease: a randomised clinical trial.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Systemic manifestations and comorbidities of COPD.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Recent advances in COPD: pathophysiology, respiratory physiology and clinical aspects, including comorbidities

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The COPD Biomarker Qualification Consortium (CBQC).

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Microalbuminuria, von Willebrand factor and fibrinogen levels as markers of the severity in COPD exacerbation

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased systemic inflammation is a risk factor for COPD exacerbations

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective p38alpha inhibitors clinically evaluated for the treatment of chronic inflammatory disorders

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, randomised controlled trials.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2813%2970200-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S2213-2600(13)70200-5

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 December 2017

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