(Q45385093)

English

Single mutation at the amino acid position 627 of PB2 that leads to increased virulence of an H5N1 avian influenza virus during adaptation in mice can be compensated by multiple mutations at other sites of PB2.

scientific article published on 23 April 2009

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 December 2017

Single mutation at the amino acid position 627 of PB2 that leads to increased virulence of an H5N1 avian influenza virus during adaptation in mice can be compensated by multiple mutations at other sites of PB2. (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

avian influenza

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based on heuristic

inferred from title

7

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Europe PubMed Central

PubMed publication ID

14 December 2017

author name string

Junwei Li

1

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

Musarat Ishaq

2

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

Mabiala Prudence

3

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

Xiao Xi

4

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

Tao Hu

5

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Europe PubMed Central

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14 December 2017

Qingzhen Liu

6

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Europe PubMed Central

PubMed publication ID

14 December 2017

publication date

23 April 2009

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Europe PubMed Central

PubMed publication ID

14 December 2017

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Europe PubMed Central

PubMed publication ID

14 December 2017

144

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Europe PubMed Central

PubMed publication ID

14 December 2017

1-2

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Europe PubMed Central

PubMed publication ID

14 December 2017

123-129

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Europe PubMed Central

PubMed publication ID

14 December 2017

An avian influenza H5N1 virus that binds to a human-type receptor.

1 reference

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7 January 2021

Evolution of cell recognition by viruses

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7 January 2021

Replication of avian influenza viruses in humans

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Inhibition of the influenza virus RNA-dependent RNA polymerase by antisera directed against the carboxy-terminal region of the PB2 subunit

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7 January 2021

Genetic analysis of mouse-adapted influenza A virus identifies roles for the NA, PB1, and PB2 genes in virulence

1 reference

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7 January 2021

Pattern of mutation in the genome of influenza A virus on adaptation to increased virulence in the mouse lung: identification of functional themes

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7 January 2021

Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome

1 reference

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7 January 2021

Differential polymerase activity in avian and mammalian cells determines host range of influenza virus

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7 January 2021

The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host.

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7 January 2021

Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virus

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7 January 2021

Lethality to ferrets of H5N1 influenza viruses isolated from humans and poultry in 2004.

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7 January 2021

Restrictions to the adaptation of influenza a virus h5 hemagglutinin to the human host.

1 reference

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7 January 2021

Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses

1 reference

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7 January 2021

Universal primer set for the full-length amplification of all influenza A viruses

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7 January 2021

A DNA transfection system for generation of influenza A virus from eight plasmids

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7 January 2021

A single-amino-acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice

1 reference

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7 January 2021

Molecular correlates of influenza A H5N1 virus pathogenesis in mice

1 reference

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7 January 2021

Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

Molecular and pathological characterization of two H5N1 avian influenza viruses isolated from wild ducks

1 reference

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7 January 2021

Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model

1 reference

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7 January 2021

Influence of the host cell on influenza virus replication

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

Recent H5N1 avian influenza A virus increases rapidly in virulence to mice after a single passage in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

Genetic analysis of the compatibility between polymerase proteins from human and avian strains of influenza A viruses

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

Host range restriction and pathogenicity in the context of influenza pandemic.

1 reference

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7 January 2021

The role of RNA segment 1 in an in vitro host restriction occurring in an avian influenza virus mutant

1 reference

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7 January 2021

Receptor determinants of human and animal influenza virus isolates: differences in receptor specificity of the H3 hemagglutinin based on species of origin

1 reference

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7 January 2021

The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04.

1 reference

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7 January 2021

Lethal H5N1 influenza viruses escape host anti-viral cytokine responses

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

PB2 amino acid at position 627 affects replicative efficiency, but not cell tropism, of Hong Kong H5N1 influenza A viruses in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

Adaptation of an H7N7 equine influenza A virus in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

Characterization of the 1918 influenza virus polymerase genes

1 reference

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7 January 2021

Sequences in influenza A virus PB2 protein that determine productive infection for an avian influenza virus in mouse and human cell lines

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

Inefficient transmission of H5N1 influenza viruses in a ferret contact model

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

Use of single-gene reassortant viruses to study the role of avian influenza A virus genes in attenuation of wild-type human influenza A virus for squirrel monkeys and adult human volunteers

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

based on heuristic

inferred from DOI database lookup

Biological heterogeneity, including systemic replication in mice, of H5N1 influenza A virus isolates from humans in Hong Kong

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

based on heuristic

inferred from DOI database lookup

Virulence of avian influenza A viruses for squirrel monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

based on heuristic

inferred from DOI database lookup

A single amino acid in the PB2 gene of influenza A virus is a determinant of host range.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2009.04.008

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.VIRUSRES.2009.04.008

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

ResearchGate publication ID

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