(Q45411485)

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Human immunodeficiency virus (HIV) type 1 Vpr induces differential regulation of T cell costimulatory molecules: direct effect of Vpr on T cell activation and immune function

scientific article published on 4 October 2006

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Europe PubMed Central

PubMed publication ID

14 December 2017

Human immunodeficiency virus (HIV) type 1 Vpr induces differential regulation of T cell costimulatory molecules: direct effect of Vpr on T cell activation and immune function (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

immune function

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based on heuristic

inferred from title

Velpandi Ayyavoo

3

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

author name string

Narasimhan J Venkatachari

1

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

Biswanath Majumder

2

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Europe PubMed Central

PubMed publication ID

14 December 2017

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publication date

4 October 2006

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Europe PubMed Central

PubMed publication ID

14 December 2017

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Europe PubMed Central

PubMed publication ID

14 December 2017

358

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Europe PubMed Central

PubMed publication ID

14 December 2017

2

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Europe PubMed Central

PubMed publication ID

14 December 2017

347-356

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

1 reference

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HIV accessory proteins and surviving the host cell

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HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor kappa B.

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Incorporation of Vpr into human immunodeficiency virus type 1 requires a direct interaction with the p6 domain of the p55 gag precursor

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Presence of HIV-1 Gag-specific IFN-gamma+IL-2+ and CD28+IL-2+ CD4 T cell responses is associated with nonprogression in HIV-1 infection

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Blocking HIV-1 Vif restores a natural mechanism of intracellular antiviral defense.

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HIV's evasion of the cellular immune response

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Dual role of the HIV-1 vpr protein in the modulation of the apoptotic response of T cells.

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Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength

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HIV-1 regulatory/accessory genes: keys to unraveling viral and host cell biology

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Clustering of T cell ligands on artificial APC membranes influences T cell activation and protein kinase C theta translocation to the T cell plasma membrane.

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Phorbol ester and diacylglycerol induce protein phosphorylation at tyrosine

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Antigen recognition and presentation by dendritic cells

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Human cytomegalovirus attenuates interleukin-1beta and tumor necrosis factor alpha proinflammatory signaling by inhibition of NF-kappaB activation

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Inhibition of the NF-kappaB pathway by varicella-zoster virus in vitro and in human epidermal cells in vivo.

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CTLA-4 upregulation during HIV infection: association with anergy and possible target for therapeutic intervention

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Vpu Exerts a Positive Effect on HIV-1 Infectivity by Down-modulating CD4 Receptor Molecules at the Surface of HIV-1-producing Cells

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Large-scale production of CD4+ T cells from HIV-1-infected donors after CD3/CD28 costimulation

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Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions

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Ultraviolet irradiation suppresses T cell activation via blocking TCR-mediated ERK and NF-kappa B signaling pathways.

1 reference

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Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis

1 reference

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Human immunodeficiency virus type 1 Vpr impairs dendritic cell maturation and T-cell activation: implications for viral immune escape

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Mini‐review: Regulation of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross‐priming and direct priming?

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HIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cells

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7 January 2021

HIV-1 Vpr inhibits the maturation and activation of macrophages and dendritic cells in vitro

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Reduction of IFN-g and IL-2 production by peripheral lymphocytes of HIV-exposed seronegative subjects

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Selective induction of high avidity CTL by altering the balance of signals from APC.

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Impaired IFN-gamma production by viral immunodominant peptide-specific tetramer+ CD8+ T cells in HIV-1 infected patients is not secondary to HAART

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The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation.

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Modulation of susceptibility to HIV-1 infection by the cytotoxic T lymphocyte antigen 4 costimulatory molecule.

1 reference

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Negative feedback of T cell activation through inhibitory adapters and costimulatory receptors

1 reference

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Modulation of cell surface protein expression by infection with HIV-1.

1 reference

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Enhanced expression of CTLA-4 (CD152) on CD4+ T cells in HIV infection.

1 reference

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Dysregulation of CD28 and CTLA-4 expression by CD4 T cells from previously immunodeficient HIV-infected patients with sustained virological responses to highly active antiretroviral therapy

1 reference

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Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta

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Role of HIV-1 Vpr in AIDS pathogenesis: relevance and implications of intravirion, intracellular and free Vpr.

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Synthetic Vpr protein activates activator protein-1, c-Jun N-terminal kinase, and NF-kappaB and stimulates HIV-1 transcription in promonocytic cells and primary macrophages

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Gene Defects Clustered at the C-Terminus of the vpr Gene of HIV-1 in Long-Term Nonprogressing Mother and Child Pair:In VivoEvolution of vpr Quasispecies in Blood and Plasma

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Direct binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I trafficking

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Human immunodeficiency virus type 1 (HIV-1) Vpr functions as an immediate-early protein during HIV-1 infection

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Extracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.VIROL.2006.08.030

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 December 2017

ResearchGate publication ID

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