(Q45639318)

14 December 2017

title

Cardiac Na+-Ca2+ exchanger: dynamics of Ca2+-dependent activation and deactivation in intact myocytes (English)

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14 December 2017

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14 December 2017

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14 December 2017

Kenneth S Ginsburg

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14 December 2017

language of work or name

English

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publication date

11 February 2013

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14 December 2017

published in

Journal of Physiology

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14 December 2017

volume

591

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14 December 2017

issue

8

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14 December 2017

page(s)

2067-2086

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Can the sodium-calcium exchanger initiate or suppress calcium sparks in cardiac myocytes?

14 December 2017

cites work

1 reference

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Data-based theoretical identification of subcellular calcium compartments and estimation of calcium dynamics in cardiac myocytes

29 September 2018

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Intracellular [Na(+)] modulates synergy between Na(+)/Ca (2+) exchanger and L-type Ca (2+) current in cardiac excitation-contraction coupling during action potentials

29 September 2018

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Proton-sensing Ca2+ binding domains regulate the cardiac Na+/Ca2+ exchanger

29 September 2018

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Ca2+-dependent structural rearrangements within Na+-Ca2+ exchanger dimers

29 September 2018

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Sodium-calcium exchange is essential for effective triggering of calcium release in mouse heart

29 September 2018

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Steady-state coupling of plasma membrane calcium entry to extrusion revealed by novel L-type calcium channel block

29 September 2018

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Allosteric activation of Na+-Ca2+ exchange by L-type Ca2+ current augments the trigger flux for SR Ca2+ release in ventricular myocytes

29 September 2018

1 reference

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The second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis

29 September 2018

1 reference

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The role of the Na+/Ca2+ exchangers in Ca2+ dynamics in ventricular myocytes

29 September 2018

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Simulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials

29 September 2018

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Three-dimensional distribution of cardiac Na+-Ca2+ exchanger and ryanodine receptor during development

29 September 2018

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Na/Ca exchange: regulator of intracellular calcium and source of arrhythmias in the heart.

29 September 2018

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Structural basis for Ca2+ regulation in the Na+/Ca2+ exchanger

29 September 2018

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Na:Ca stoichiometry and cytosolic Ca-dependent activation of NCX in intact cardiomyocytes

29 September 2018

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Sodium-calcium exchange does not require allosteric calcium activation at high cytosolic sodium concentrations.

29 September 2018

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Molecular control of cardiac sodium homeostasis in health and disease.

29 September 2018

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Na"Fuzzy space": does it exist, and is it important in ischemic injury?

29 September 2018

1 reference

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Sodium/calcium exchanger: influence of metabolic regulation on ion carrier interactions

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Synergistic interactions between Ca2+ entries through L-type Ca2+ channels and Na+-Ca2+ exchanger in normal and failing rat heart

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Cardiac sodium-calcium exchanger is regulated by allosteric calcium and exchanger inhibitory peptide at distinct sites

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

New insights into the molecular and cellular workings of the cardiac Na+/Ca2+ exchanger

29 September 2018

1 reference

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A mathematical treatment of integrated Ca dynamics within the ventricular myocyte.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Conformational changes of the Ca(2+) regulatory site of the Na(+)-Ca(2+) exchanger detected by FRET.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Calcium-dependent regulation of calcium efflux by the cardiac sodium/calcium exchanger

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Multiple transport modes of the cardiac Na+/Ca2+ exchanger.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Localization and function of the Na+/Ca2+-exchanger in normal and detubulated rat cardiomyocytes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Allosteric activation of sodium-calcium exchange activity by calcium: persistence at low calcium concentrations

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Na/K pump current and [Na](i) in rabbit ventricular myocytes: local [Na](i) depletion and Na buffering

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Involvement of Ca2+ buffering and Na+/Ca2+ exchange in the positive staircase of contraction in guinea-pig ventricular myocytes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Na(+)-Ca(2+) exchange current and submembrane [Ca(2+)] during the cardiac action potential

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Rapid inhibition of the Na+-K+ pump affects Na+-Ca2+ exchanger-mediated relaxation in rabbit ventricular myocytes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Local regulation of the threshold for calcium sparks in rat ventricular myocytes: role of sodium-calcium exchange.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

The control of Ca release from the cardiac sarcoplasmic reticulum: regulation versus autoregulation.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Regulation of Na+/Ca2+ exchange activity by cytosolic Ca2+ in transfected Chinese hamster ovary cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Na+/Ca2+ exchange and cellular Ca2+ homeostasis

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Na-Ca exchange and the trigger for sarcoplasmic reticulum Ca release: studies in adult rabbit ventricular myocytes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Interaction of the Na+-K+ pump and Na+-Ca2+ exchange via [Na+]i in a restricted space of guinea-pig ventricular cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Low efficiency of Ca2+ entry through the Na(+)-Ca2+ exchanger as trigger for Ca2+ release from the sarcoplasmic reticulum. A comparison between L-type Ca2+ current and reverse-mode Na(+)-Ca2+ exchange

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Transport and regulation of the cardiac Na(+)-Ca2+ exchanger, NCX1. Comparison between Ca2+ and Ba2+

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Barium influx mediated by the cardiac sodium-calcium exchanger in transfected Chinese hamster ovary cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Rapid charge translocation by the cardiac Na(+)-Ca2+ exchanger after a Ca2+ concentration jump

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Regulation of cardiac Na+,Ca2+ exchange and KATP potassium channels by PIP2.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Multiple functional states of the cardiac Na(+)-Ca2+ exchanger. Whole-cell, native-excised, and cloned-excised properties

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Comparison of subsarcolemmal and bulk calcium concentration during spontaneous calcium release in rat ventricular myocytes.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Identification of the high affinity Ca(2+)-binding domain of the cardiac Na(+)-Ca2+ exchanger

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Regulation of the cardiac Na(+)-Ca2+ exchanger by Ca2+. Mutational analysis of the Ca(2+)-binding domain

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

The stoichiometry of the cardiac sodium-calcium exchange system.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Transmembrane Na+ and Ca2+ electrochemical gradients in cardiac muscle and their relationship to force development

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Regulation of Ca2+-pumping ATPase of heart sarcolemma by a phosphorylation-dephosphorylation Process

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Na-Ca exchange current in mammalian heart cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Mechanisms contributing to the cardiac inotropic effect of Na pump inhibition and reduction of extracellular Na.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Sodium-calcium exchange current. Dependence on internal Ca and Na and competitive binding of external Na and Ca.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Regulation and deregulation of cardiac Na(+)-Ca2+ exchange in giant excised sarcolemmal membrane patches

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Cytosolic free Ca2+ during operation of sodium-calcium exchange in guinea-pig heart cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)-Ca2+ exchanger

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Control of the Na-Ca exchanger in isolated heart cells. II. Beat-dependent activation in normal cells by intracellular calcium

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Steady-state and dynamic properties of cardiac sodium-calcium exchange. Secondary modulation by cytoplasmic calcium and ATP

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

The giant cardiac membrane patch method: stimulation of outward Na(+)-Ca2+ exchange current by MgATP

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Calcium influx in internally dialyzed squid giant axons

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

The generation of electric currents in cardiac fibers by Na/Ca exchange

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3634520

Regulation kinetics of Na+-Ca2+ exchange current in guinea-pig ventricular myocytes.

29 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.252080

An ATP-dependent Ca2+-pumping system in dog heart sarcolemma

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2013.252080

Inactivation of outward Na(+)-Ca2+ exchange current in guinea-pig ventricular myocytes

21 January 2018

1 reference

12 December 2020

Modulation of Na+-Ca2+ exchange in sarcolemmal vesicles by intravesicular Ca2+

1 reference

12 December 2020

The role of sarcolemmal Ca2+-ATPase in the regulation of resting calcium concentration in rat ventricular myocytes

1 reference

12 December 2020

Control of the Na-Ca exchanger in isolated heart cells. I. Induction of Na-Na exchange in sodium-loaded cells by intracellular calcium

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12 December 2020

Cytoplasmic sodium, calcium and free energy change of the Na+/Ca2+-exchanger in rat ventricular myocytes

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12 December 2020

The quantitative relationship between twitch tension and intracellular sodium activity in sheep cardiac Purkinje fibres

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12 December 2020

Kinetic and equilibrium properties of regulatory calcium sensors of NCX1 protein

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12 December 2020

KB-R7943 block of Ca(2+) influx via Na(+)/Ca(2+) exchange does not alter twitches or glycoside inotropy but prevents Ca(2+) overload in rat ventricular myocytes

1 reference

12 December 2020

Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms

1 reference

12 December 2020

Diastolic SR Ca efflux in atrial pacemaker cells and Ca-overloaded myocytes

1 reference

12 December 2020

Cardiac submembrane [Na+] transients sensed by Na+-Ca2+ exchange current

1 reference

12 December 2020

Microdomain [Ca²⁺] near ryanodine receptors as reported by L-type Ca²⁺ and Na+/Ca²⁺ exchange currents

1 reference

12 December 2020

Measurement of calcium entry and exit in quiescent rat ventricular myocytes

1 reference

12 December 2020

Intracellular calcium and sodium activity in sheep heart Purkinje fibres. Effect of changes of external sodium and intracellular pH

1 reference

12 December 2020

The sarcolemmal mechanisms involved in the control of diastolic intracellular calcium in isolated rat cardiac trabeculae

1 reference

12 December 2020

Na-Ca exchange is required for rest-decay but not for rest-potentiation of twitches in rabbit and rat ventricular myocytes

1 reference

12 December 2020

Sodium-calcium exchange and store-dependent calcium influx in transfected chinese hamster ovary cells expressing the bovine cardiac sodium-calcium exchanger. Acceleration of exchange activity in thapsigargin-treated cells

1 reference

12 December 2020

A novel, rapid and reversible method to measure Ca buffering and time-course of total sarcoplasmic reticulum Ca content in cardiac ventricular myocytes

1 reference

12 December 2020

Cooperative interaction between Ca2+ binding sites in the hydrophilic loop of the Na(+)-Ca2+ exchanger

1 reference

12 December 2020

Ca2+ regulation in the Na+/Ca2+ exchanger involves two markedly different Ca2+ sensors

1 reference

12 December 2020

10.1113/JPHYSIOL.2013.252080

Identifiers

DOI

1 reference

14 December 2017

0 references

1 reference