(Q45668619)

English

Optimal design of a single recombinant adeno-associated virus derived from serotypes 1 and 2 to achieve more tightly regulated transgene expression from nonhuman primate muscle

scientific article published in March 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

15 December 2017

Optimal design of a single recombinant adeno-associated virus derived from serotypes 1 and 2 to achieve more tightly regulated transgene expression from nonhuman primate muscle (English)

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Europe PubMed Central

PubMed publication ID

15 December 2017

Thibaut Larcher

2

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15 December 2017

author name string

Pierre Chenuaud

1

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15 December 2017

Joseph E Rabinowitz

3

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15 December 2017

Nathalie Provost

4

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15 December 2017

Béatrice Joussemet

5

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15 December 2017

Hermann Bujard

6

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15 December 2017

Richard J S Samulski

7

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15 December 2017

David Favre

8

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15 December 2017

Philippe Moullier

9

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15 December 2017

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1 March 2004

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15 December 2017

Molecular Therapy

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15 December 2017

9

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15 December 2017

3

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15 December 2017

410-418

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15 December 2017

Adeno-associated virus vectors for gene therapy: more pros than cons?

1 reference

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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Ligand-inducible and liver-specific target gene expression in transgenic mice

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Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

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A humanized system for pharmacologic control of gene expression

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Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus

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Mechanisms underlying expression of Tn10 encoded tetracycline resistance

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Transcriptional activation by tetracyclines in mammalian cells

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Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

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Novel transcriptional regulatory signals in the adeno-associated virus terminal repeat A/D junction element

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Enhanced expression of transgenes from adeno-associated virus vectors with the woodchuck hepatitis virus posttranscriptional regulatory element: implications for gene therapy

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Efficient selection for high-expression transfectants with a novel eukaryotic vector

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Novel tools for production and purification of recombinant adenoassociated virus vectors

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Immediate and long-term safety of recombinant adeno-associated virus injection into the nonhuman primate muscle

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Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

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7 January 2021

Factors influencing recombinant adeno-associated virus production

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Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1.

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7 January 2021

Controlled transgene expression by E1-E4-defective adenovirus vectors harbouring a "tet-on" switch system

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Versatile retrovirus vector systems for regulated gene expression in vitro and in vivo.

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A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells

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Cell-type-specific and regulatable transgenesis in the adult brain: adenovirus-encoded combined transcriptional targeting and inducible transgene expression

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Switching on and off transgene expression within lactotrophic cells in the anterior pituitary gland in vivo

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Tight control of gene expression by a helper-dependent adenovirus vector carrying the rtTA2(s)-M2 tetracycline transactivator and repressor system.

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Recombinant AAV-mediated delivery of a tet-inducible reporter gene to the rat retina

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Tightly regulated long-term erythropoietin expression in vivo using tet-inducible recombinant adeno-associated viral vectors

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Stringent control of gene expression in vivo by using novel doxycycline-dependent trans-activators

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Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances

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Construction of an rtTA2(s)-m2/tts(kid)-based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and non-human primates

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7 January 2021

Quantitative analysis of the packaging capacity of recombinant adeno-associated virus

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Doxycycline-regulated lentiviral vector system with a novel reverse transactivator rtTA2S-M2 shows a tight control of gene expression in vitro and in vivo

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7 January 2021

Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors

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7 January 2021

Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.

1 reference

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10.1016/J.YMTHE.2003.12.015

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

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