(Q45735456)

15 December 2017

title

CD8-deficient SJL mice display enhanced susceptibility to Theiler's virus infection and increased demyelinating pathology (English)

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15 December 2017

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W S Begolka

1

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15 December 2017

L M Haynes

2

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15 December 2017

J K Olson

3

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15 December 2017

J Padilla

4

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15 December 2017

K L Neville

5

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15 December 2017

M Dal Canto

6

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15 December 2017

J Palma

7

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15 December 2017

B S Kim

8

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15 December 2017

S D Miller

9

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15 December 2017

publication date

1 October 2001

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15 December 2017

published in

Journal of NeuroVirology

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15 December 2017

volume

7

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15 December 2017

issue

5

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15 December 2017

page(s)

409-420

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https://scigraph.springernature.com/pub.10.1080/135502801753170264

15 December 2017

exact match

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cites work

Abrogation of resistance to Theiler's virus-induced demyelination in H-2b mice deficient in beta 2-microglobulin

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12 December 2020

Study of the mechanisms by which CD4+ T cells contribute to protection in Theiler's murine encephalomyelitis.

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12 December 2020

Role of individual T-cell epitopes of Theiler's virus in the pathogenesis of demyelination correlates with the ability to induce a Th1 response.

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12 December 2020

Split tolerance of Th1 and Th2 cells in tolerance to Theiler's murine encephalomyelitis virus

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12 December 2020

Persistent infection of oligodendrocytes in Theiler's virus‐induced encephalomyelitis

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12 December 2020

Cytotoxic T cells isolated from the central nervous systems of mice infected with Theiler's virus

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12 December 2020

In vivo administration of interleukin-2 protects susceptible mice from Theiler's virus persistence.

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12 December 2020

Demyelination induced by Theiler's virus: influence of the H-2 haplotype

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12 December 2020

Interleukin (IL) 4, in the absence of antigen stimulation, induces an anergy-like state in differentiated CD8+ TC1 cells: loss of IL-2 synthesis and autonomous proliferation but retention of cytotoxicity and synthesis of other cytokines.

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12 December 2020

Partial suppression of Theiler's virus-induced demyelination in vivo by administration of monoclonal antibodies to immune-response gene products (Ia antigens).

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12 December 2020

Central Nervous System Immunity in Mice Infected with Theiler's Virus. I. Local Neutralizing Antibody Response

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12 December 2020

Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in mice is influenced by the H-2D region: correlation with TEMV-specific delayed-type hypersensitivity

1 reference

12 December 2020

Type 1 and type 2: a fundamental dichotomy for all T-cell subsets

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12 December 2020

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

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12 December 2020

Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines.

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12 December 2020

Theiler's virus infection of beta 2-microglobulin-deficient mice

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12 December 2020

Theiler's virus antigen detected in mouse spinal cord 21/2 years after infection

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12 December 2020

Multiple sclerosis. More genes versus environment

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12 December 2020

Theiler's virus infection induces a specific cytotoxic T lymphocyte response

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12 December 2020

Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis

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12 December 2020

Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis

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12 December 2020

CD8(+) T cells from Theiler's virus-resistant BALB/cByJ mice downregulate pathogenic virus-specific CD4(+) T cells

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12 December 2020

Susceptibility to Theiler's virus-induced demyelination. Mapping of the gene within the H-2D region

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12 December 2020

Theiler's virus in brain cell cultures: lysis of neurons and oligodendrocytes and persistence in astrocytes and macrophages

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12 December 2020

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

1 reference

12 December 2020

Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus-induced demyelinating disease. VI. Potentiation of demyelination with and characterization of an immunopathologic CD4+ T cell line specific for an immunodominant VP2 ep

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12 December 2020

Cellular reservoirs for coronavirus infection of the brain in beta2-microglobulin knockout mice.

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12 December 2020

Theiler's virus-associated antigens on the surfaces of cultured glial cells

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12 December 2020

Theiler's virus infection of perforin-deficient mice.

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12 December 2020

Inhibition of Theiler's virus-mediated demyelination by peripheral immune tolerance induction

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12 December 2020

The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases

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12 December 2020

Susceptibility of inbred mice to chronic central nervous system infection by Theiler's murine encephalomyelitis virus

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12 December 2020

An early, abundant cytotoxic T-lymphocyte response against Theiler's virus is critical for preventing viral persistence

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12 December 2020

Characterization of Theiler's murine encephalomyelitis virus (TMEV)-specific delayed-type hypersensitivity responses in TMEV-induced demyelinating disease: correlation with clinical signs.

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12 December 2020

VP1 and VP2 capsid proteins of Theiler's virus are targets of H-2D-restricted cytotoxic lymphocytes in the central nervous system of B10 mice

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12 December 2020

Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles

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12 December 2020

The functional role of CD8+ T helper type 2 cells

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12 December 2020

Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.

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12 December 2020

Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient mice

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12 December 2020

Monoclonal anti-I-A antibody reverses chronic paralysis and demyelination in Theiler's virus-infected mice: critical importance of timing of treatment

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12 December 2020

Adoptively transferred CD8+ T lymphocytes provide protection against TMEV-induced demyelinating disease in BALB/c mice

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12 December 2020

CD4(+) and CD8(+) T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosis

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12 December 2020

Hierarchy of effects of the MHC and T cell receptor beta-chain genes in susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease

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12 December 2020

Epidemiologic evidence for multiple sclerosis as an infection

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12 December 2020

CD8Tc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions

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12 December 2020

Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading

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12 December 2020

Cytotropism of Theiler's murine encephalomyelitis viruses in oligodendrocyte-enriched cultures

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12 December 2020

Flow cytometric and functional analyses of central nervous system-infiltrating cells in SJL/J mice with Theiler's virus-induced demyelinating disease. Evidence for a CD4+ T cell-mediated pathology.

1 reference

12 December 2020

Successful therapy of Theiler's virus-induced demyelination (DA strain) with monoclonal anti-Lyt-2 antibody

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12 December 2020

The effect of L3T4 T cell depletion on the pathogenesis of Theiler's murine encephalomyelitis virus infection in CBA mice

1 reference

12 December 2020

Suppressive effect on Theiler's murine encephalomyelitis virus-induced demyelinating disease by the administration of anti-IL-12 antibody

1 reference

12 December 2020

Class I-deficient resistant mice intracerebrally inoculated with Theiler's virus show an increased T cell response to viral antigens and susceptibility to demyelination

1 reference

12 December 2020

10.1080/135502801753170264

Identifiers

DOI

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Dimensions Publication ID

15 December 2017

1035389125

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PMC publication ID

7094986

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1 reference