(Q45736386)

English

Neuroprotective effects of paeoniflorin, but not the isomer albiflorin, are associated with the suppression of intracellular calcium and calcium/calmodulin protein kinase II in PC12 cells

scientific article published on 22 May 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Neuroprotective effects of paeoniflorin, but not the isomer albiflorin, are associated with the suppression of intracellular calcium and calcium/calmodulin protein kinase II in PC12 cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

1 reference

ChEBI release 2020-05-28

author name string

Di Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Qing-Rong Tan

2

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Zhang-Jin Zhang

3

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Europe PubMed Central

PubMed publication ID

15 December 2017

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publication date

22 May 2013

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Europe PubMed Central

PubMed publication ID

15 December 2017

Journal of Molecular Neuroscience

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Europe PubMed Central

PubMed publication ID

15 December 2017

51

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Europe PubMed Central

PubMed publication ID

15 December 2017

2

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Europe PubMed Central

PubMed publication ID

15 December 2017

581-590

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Europe PubMed Central

PubMed publication ID

15 December 2017

https://scigraph.springernature.com/pub.10.1007/s12031-013-0031-7

0 references

Hydrogen peroxide modulates whole cell Ca2+ currents through L-type channels in cultured rat dentate granule cells

1 reference

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Calcium signaling and neurodegenerative diseases

1 reference

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Paeoniflorin, a potent natural compound, protects PC12 cells from MPP+ and acidic damage via autophagic pathway

1 reference

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Proteins of the bcl-2 family in apoptosis signalling: from mechanistic insights to therapeutic opportunities.

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Mitochondrial Ca(2+) and apoptosis

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GSK3 signalling in neural development

1 reference

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Hexane extract from Polygonum multiflorum attenuates glutamate-induced apoptosis in primary cultured cortical neurons

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Influence of Paeonia lactiflora roots extract on cAMP-phosphodiesterase activity and related anti-inflammatory action

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Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

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Adipose-derived mesenchymal stem cells protect PC12 cells from glutamate excitotoxicity-induced apoptosis by upregulation of XIAP through PI3-K/Akt activation.

1 reference

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Protective effects of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via antioxidant mechanisms and Ca(2+) antagonism

1 reference

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Mitochondrial dysfunction and glutamate excitotoxicity studied in primary neuronal cultures

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Scutellarin exerts its anti-hypertrophic effects via suppressing the Ca2+-mediated calcineurin and CaMKII signaling pathways

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Calmodulin and CaMKII as molecular switches for cardiac ion channels.

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Released nucleotides amplify the cilium-dependent, flow-induced [Ca2+]i response in MDCK cells.

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The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis

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Cytoskeletal organization following cannabinoid treatment in undifferentiated and differentiated PC12 cells

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Neuroprotective effects of biochanin A against glutamate-induced cytotoxicity in PC12 cells via apoptosis inhibition

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Mitochondria at the crossroad of apoptotic cell death

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Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways.

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Rescue of neurological deficits in a mouse model for Angelman syndrome by reduction of alphaCaMKII inhibitory phosphorylation.

1 reference

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Glutamate-induced c-Jun expression in neuronal PC12 cells: the effects of ketamine and propofol

1 reference

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Paeoniflorin, a natural neuroprotective agent, modulates multiple anti-apoptotic and pro-apoptotic pathways in differentiated PC12 cells.

1 reference

https://api.crossref.org/works/10.1007%2FS12031-013-0031-7

21 January 2018

CaMKII locally encodes L-type channel activity to signal to nuclear CREB in excitation-transcription coupling

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21 January 2018

Chemical constituents and bioactivities of plants from the genus Paeonia

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Phosphorylation of tau protein to sites found in Alzheimer's disease brain is catalyzed by Ca2+/calmodulin-dependent protein kinase II as demonstrated tandem mass spectrometry

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21 January 2018

Age-related expression of calcium/calmodulin-dependent protein kinase II A in the hippocampus and cerebral cortex of senescence accelerated mouse prone/8 mice is modulated by anti-Alzheimer's disease drugs.

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Kangen-karyu improves memory deficit caused by aging through normalization of neuro-plasticity-related signaling system and VEGF system in the brain

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Mitochondrial Regulation of Apoptosis

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Protective effect of paeoniflorin on irradiation-induced cell damage involved in modulation of reactive oxygen species and the mitogen-activated protein kinases

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Protective effect of paeoniflorin against oxidative stress in human retinal pigment epithelium in vitro

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Protective effects of peony glycosides against corticosterone-induced cell death in PC12 cells through antioxidant action

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Therapeutic effects of combination of paeoniflorin and albiflorin from Paeonia radix on radiation and chemotherapy-induced myelosuppression in mice and rabbits

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Evidence for redox regulation of cytochrome C release during programmed neuronal death: antioxidant effects of protein synthesis and caspase inhibition.

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Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

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Modulation of programmed cell death by medicinal plants

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The inhibition of ERK activation mediates the protection of necrostatin-1 on glutamate toxicity in HT-22 cells

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[A review on the pharmacology of Paeonia lactiflora and its chemical components]

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12031-013-0031-7

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

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