(Q45738405)

English

A growth and latency compromised herpes simplex virus type 2 mutant (ICP10DeltaPK) has prophylactic and therapeutic protective activity in guinea pigs

scientific article published in February 2001

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scholarly article

1 reference

Europe PubMed Central

15 December 2017

A growth and latency compromised herpes simplex virus type 2 mutant (ICP10DeltaPK) has prophylactic and therapeutic protective activity in guinea pigs (English)

1 reference

Europe PubMed Central

15 December 2017

author name string

Wachsman M

1

1 reference

Europe PubMed Central

15 December 2017

Kulka M

2

1 reference

Europe PubMed Central

15 December 2017

Smith CC

3

1 reference

Europe PubMed Central

15 December 2017

Aurelian L

4

1 reference

Europe PubMed Central

15 December 2017

language of work or name

0 references

publication date

1 February 2001

1 reference

Europe PubMed Central

15 December 2017

number of pages

12

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

15 December 2017

19

1 reference

Europe PubMed Central

15 December 2017

15-16

1 reference

Europe PubMed Central

15 December 2017

1879-1890

1 reference

Europe PubMed Central

15 December 2017

Herpes simplex virus type 2 in the United States, 1976 to 1994.

1 reference

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7 January 2021

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Clinical and subclinical HSV infection resulting from exposure to asymptomatic patients

1 reference

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7 January 2021

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Evidence of latency and reactivation of both herpes simplex virus (HSV)-1 and HSV-2 in the genital region

1 reference

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7 January 2021

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Recombinant glycoprotein vaccine for the prevention of genital HSV-2 infection: two randomized controlled trials. Chiron HSV Vaccine Study Group

1 reference

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7 January 2021

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Cutaneous ultraviolet radiation inhibits herpes simplex virus-induced lymphoproliferation in latently infected subjects

1 reference

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7 January 2021

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A pathogenic role of Th2 responses on the severity of encephalomyelitis induced in mice by herpes simplex virus type 2 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

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Expression of the first 811 nucleotides of the herpes simplex virus type 1 latency-associated transcript (LAT) partially restores wild-type spontaneous reactivation to a LAT-null mutant.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A herpes simplex virus transcript abundant in latently infected neurons is dispensable for establishment of the latent state

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Herpes simplex virus latent RNA (LAT) is not required for latent infection in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantity of latency-associated transcript produced by herpes simplex virus is not predictive of the frequency of experimental recurrent genital herpes

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of a nerve growth factor-inducible cellular activity that enhances herpes simplex virus type 1 gene expression and replication of an ICP0 null mutant in cells of neural lineage.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in the 5' end of the herpes simplex virus type 2 latency-associated transcript (LAT) promoter affect LAT expression in vivo but not the rate of spontaneous reactivation of genital herpes

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Vaccine potential of a herpes simplex virus type 2 mutant deleted in the PK domain of the large subunit of ribonucleotide reductase (ICP10).

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A herpes simplex virus ribonucleotide reductase deletion mutant is defective for productive acute and reactivatable latent infections of mice and for replication in mouse cells

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Delection of the herpes simplex virus type 1 ribonucleotide reductase gene alters virulence and latency in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for virus growth and neoplastic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic sequences homologous to the protein kinase region of the bifunctional herpes simplex virus type 2 protein ICP10.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunity to herpes simplex virus type 2: cell-mediated immunity in latently infected guinea pigs

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Protection of guinea pigs from primary and recurrent herpes simplex virus (HSV) type 2 cutaneous disease with vaccinia virus recombinants expressing HSV glycoprotein D.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Vaccination with recombinant herpes simplex virus glycoproteins: protection against initial and recurrent genital herpes

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Vaccinating guinea pigs with recombinant glycoprotein D of herpes simplex virus in an efficacious adjuvant formulation elicits protection against vaginal infection

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Construction and characterization of a replication-defective herpes simplex virus 2 ICP8 mutant strain and its use in immunization studies in a guinea pig model of genital disease

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of the herpes simplex virus type 2 latency-associated transcript enhances spontaneous reactivation of genital herpes in latently infected guinea pigs

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of acyclovir on genital infection with herpes simplex virus types 1 and 2 in the guinea pig

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The latent herpes simplex virus type 1 genome copy number in individual neurons is virus strain specific and correlates with reactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunization of experimental animals with reconstituted glycoprotein mixtures of herpes simplex virus 1 and 2: protection against challenge with virulent virus

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Intranasal immunization with recombinant gD2 reduces disease severity and mortality following genital challenge with herpes simplex virus type 2 in guinea pigs

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Intranasal immunization of mice with herpes simplex virus type 2 recombinant gD2: the effect of adjuvants on mucosal and serum antibody responses

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Herpes simplex virus vaccines

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Virulence of and establishment of latency by genetically engineered deletion mutants of herpes simplex virus 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunization with recombinant varicella-zoster virus expressing herpes simplex virus type 2 glycoprotein D reduces the severity of genital herpes in guinea pigs.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The mouse model and understanding immunity to herpes simplex virus.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Vaccination of mice with herpes simplex virus type 1 glycoprotein D DNA produces low levels of protection against lethal HSV-1 challenge

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA immunization confers protective immunity on mice challenged intravaginally with herpes simplex virus type 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleic acid vaccine encoding gD2 protects mice from herpes simplex virus type 2 disease

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of a live attenuated recombinant virus RAV 9395 as a herpes simplex virus type 2 vaccine in guinea pigs

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Protective vaccination against primary and recurrent disease caused by herpes simplex virus (HSV) type 2 using a genetically disabled HSV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A genetically inactivated herpes simplex virus type 2 (HSV-2) vaccine provides effective protection against primary and recurrent HSV-2 disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ras-GAP binding and phosphorylation by herpes simplex virus type 2 RR1 PK (ICP10) and activation of the Ras/MEK/MAPK mitogenic pathway are required for timely onset of virus growth

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Herpes simplex vegetans: atypical genital herpes infection in a patient with common variable immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Correlation between herpes simplex virus type 1 rate of reactivation from latent infection and the number of infected neurons in trigeminal ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of herpes simplex virus DNA fragments located in epidermal keratinocytes and germinative cells is associated with the development of erythema multiforme lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

AP-1 cis-response elements are involved in basal expression and Vmw110 transactivation of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10).

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunity to herpes simplex virus: virus reactivation modulates lymphokine activity

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-12 protects thermally injured mice from herpes simplex virus type 1 infection.

1 reference

https://api.crossref.org/works/10.1016%2FS0264-410X%2800%2900446-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0264-410X(00)00446-1

1 reference

Europe PubMed Central

15 December 2017

1 reference

Europe PubMed Central

15 December 2017

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