(Q45743231)

15 December 2017

title

Frequent integration of precore/core mutants of hepatitis B virus in human hepatocellular carcinoma tissues (English)

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15 December 2017

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hepatocellular carcinoma

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Zhong S

1

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15 December 2017

Chan JY

2

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15 December 2017

Yeo W

3

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15 December 2017

Tam JS

4

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15 December 2017

Johnson PJ

5

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15 December 2017

publication date

1 March 2000

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15 December 2017

Journal of Viral Hepatitis

published in

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15 December 2017

volume

7

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15 December 2017

issue

2

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15 December 2017

page(s)

115-123

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15 December 2017

The role of hepatitis B virus in the development of primary hepatocellular carcinoma: Part I.

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Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinoma

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A trans-activator function is generated by integration of hepatitis B virus preS/S sequences in human hepatocellular carcinoma DNA.

21 January 2018

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The preS2/S region of integrated hepatitis B virus DNA encodes a transcriptional transactivator

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Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma. Studies in percutaneous liver biopsies and post-mortem tissue specimens

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Hepatitis B virus DNA in the hepatocyte. A series of 160 biopsies

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Association of a precore genomic variant of hepatitis B virus with fulminant hepatitis

21 January 2018

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Fulminant hepatitis B: induction by hepatitis B virus mutants defective in the precore region and incapable of encoding e antigen

21 January 2018

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Novel pre-C/C gene mutants of hepatitis B virus in chronic active hepatitis: naturally occurring escape mutants

21 January 2018

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Replication of hepatitis B virus in a hepatocellular carcinoma

21 January 2018

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Sequence analysis of the hepatitis B virus pre-C region in hepatocellular carcinoma [HCC] and nontumoral liver tissues from HCC patients

21 January 2018

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Hepatitis B virus preC mutants in human hepatocellular carcinoma tissues

21 January 2018

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Core antigen mutations of human hepatitis B virus in hepatomas accumulate in MHC class II-restricted T cell epitopes

21 January 2018

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Precore/core mutations of hepatitis B virus in hepatocellular carcinomas developed on noncirrhotic livers

21 January 2018

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Replication capacities of natural and artificial precore stop codon mutants of hepatitis B virus: relevance of pregenome encapsidation signal

21 January 2018

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Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pre-genome encapsidation signal

21 January 2018

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Tumor suppressor genes, growth factor genes, and oncogenes in hepatitis B virus-associated hepatocellular carcinoma

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HLA-A31- and HLA-Aw68-restricted cytotoxic T cell responses to a single hepatitis B virus nucleocapsid epitope during acute viral hepatitis

21 January 2018

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Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen

21 January 2018

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Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo

21 January 2018

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Biologic properties of hepatitis B viral genomes with mutations in the precore promoter and precore open reading frame

21 January 2018

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Hepatitis B virus precore mutants are identical in carriers from various ethnic origins and are associated with a range of liver disease severity

21 January 2018

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The role of pre-core hepatitis B virus mutants on the long-term outcome of chronic hepatitis B virus hepatitis. A longitudinal study

21 January 2018

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Detection of precore hepatitis B virus mutants in asymptomatic HBsAg-positive family members

21 January 2018

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Hot-spot mutations in hepatitis B virus X gene in hepatocellular carcinoma

21 January 2018

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Wild-type levels of pregenomic RNA and replication but reduced pre-C RNA and e-antigen synthesis of hepatitis B virus with C(1653) --> T, A(1762) --> T and G(1764) --> A mutations in the core promoter

21 January 2018

1 reference

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Detection of pre-C and core region mutants of hepatitis B virus in chronic hepatitis B virus carriers

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2893.2000.00209.X

10.1046/J.1365-2893.2000.00209.X

21 January 2018

Identifiers

DOI

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15 December 2017

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15 December 2017