(Q45744166)

15 December 2017

title

RNA and DNA hydrolysis are catalyzed by the influenza virus endonuclease (English)

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15 December 2017

author name string

Klumpp K

1

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15 December 2017

Doan L

2

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15 December 2017

Roberts NA

3

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15 December 2017

Handa B

4

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15 December 2017

language of work or name

English

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publication date

1 March 2000

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15 December 2017

Journal of Biological Chemistry

published in

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15 December 2017

volume

275

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15 December 2017

issue

9

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15 December 2017

page(s)

6181-6188

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15 December 2017

Genomic RNAs of influenza viruses are held in a circular conformation in virions and in infected cells by a terminal panhandle

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RNA-dependent activation of primer RNA production by influenza virus polymerase: different regions of the same protein subunit constitute the two required RNA-binding sites

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Transfer of 5′-terminal cap of globin mRNA to influenza viral complementary RNA during transcription in vitro

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A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription

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Structure of the host-derived sequences present at the 5' ends of influenza virus mRNA.

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Selected host cell capped RNA fragments prime influenza viral RNA transcription in vivo

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Transcriptional fidelity and proofreading by RNA polymerase II.

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Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds

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Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine

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Metal ion catalysis of RNA cleavage by the influenza virus endonuclease

21 January 2018

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Influenza A virus RNA polymerase subunit PB2 is the endonuclease which cleaves host cell mRNA and functions only as the trimeric enzyme

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Inhibition of the influenza virus RNA-dependent RNA polymerase by antisera directed against the carboxy-terminal region of the PB2 subunit

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Molecular model of a eucaryotic transcription complex: functions and movements of influenza P proteins during capped RNA-primed transcription

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Binuclear Metallohydrolases

21 January 2018

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Ribonuclease P catalysis requires Mg2+ coordinated to the pro-RP oxygen of the scissile bond.

21 January 2018

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Solid phase synthesis of 5'-diphosphorylated oligoribonucleotides and their conversion to capped m7Gppp-oligoribonucleotides for use as primers for influenza A virus RNA polymerase in vitro

21 January 2018

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Elucidation of basic mechanistic and kinetic properties of influenza endonuclease using chemically synthesized RNAs

21 January 2018

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Variation in ATP requirement during influenza virus transcription

21 January 2018

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The gene structure and replication of influenza virus

21 January 2018

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The role of template-primer interactions in cleavage and initiation by the influenza virus polymerase

21 January 2018

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Identification of the cap binding protein of influenza virus.

21 January 2018

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Role of two of the influenza virus core P proteins in recognizing cap 1 structures (m7GpppNm) on RNAs and in initiating viral RNA transcription

21 January 2018

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A general two-metal-ion mechanism for catalytic RNA

21 January 2018

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Cocrystal structure of an editing complex of Klenow fragment with DNA

21 January 2018

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Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates

21 January 2018

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Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions

21 January 2018

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Construction and characterization of a bacteriophage T4 DNA polymerase deficient in 3'-->5' exonuclease activity

21 January 2018

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Functional consequences and exonuclease kinetic parameters of point mutations in bacteriophage T4 DNA polymerase

21 January 2018

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The crystal structure of flap endonuclease-1 from Methanococcus jannaschii

21 January 2018

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Functional analysis of point mutations in human flap endonuclease-1 active site

21 January 2018

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X-ray structure of the DNase I-d(GGTATACC)2 complex at 2.3 A resolution

21 January 2018

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Site-directed mutagenesis of the catalytic residues of bovine pancreatic deoxyribonuclease I.

21 January 2018

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Site-directed mutagenesis studies with EcoRV restriction endonuclease to identify regions involved in recognition and catalysis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6181

Are the 5' ends of influenza viral mRNAs synthesized in vivo donated by host mRNAs?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6181

Nonviral oligonucleotides at the 5' terminus of cytoplasmic influenza viral mRNA deduced from cloned complete genomic sequences

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6181

RNA polymerase of influenza virus. IV. Catalytic properties of the capped RNA endonuclease associated with the RNA polymerase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6181

Manganese Enzymes with Binuclear Active Sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6181

Multiple magnesium ions in the ribonuclease P reaction mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6181

A site-directed mutagenesis study to identify amino acid residues involved in the catalytic function of the restriction endonuclease EcoRV

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6181

21 January 2018

Identifiers

DOI

10.1074/JBC.275.9.6181

1 reference

15 December 2017

PubMed ID

10692410

1 reference

15 December 2017