(Q45753505)

15 December 2017

review article

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title

Clinical implications of mutations in the hepatitis B virus genome (English)

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15 December 2017

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Torre F

1

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15 December 2017

Naoumov NV

series ordinal

2

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15 December 2017

publication date

1 August 1998

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15 December 2017

European Journal of Clinical Investigation

published in

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15 December 2017

volume

28

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15 December 2017

issue

8

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15 December 2017

page(s)

604-614

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15 December 2017

Viral dynamics in hepatitis B virus infection

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Molecular epidemiology of hepatitis B virus vaccine variants in Singapore

21 January 2018

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Mutations within the S gene of hepatitis B virus transmitted from mothers to babies immunized with hepatitis B immune globulin and vaccine

21 January 2018

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A novel hepatitis B virus variant in the sera of immunized children

21 January 2018

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Is a function of the secreted hepatitis B e antigen to induce immunologic tolerance in utero?

21 January 2018

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Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection.

21 January 2018

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In vitro replication competence of a cloned hepatitis B virus variant with a nonsense mutation in the distal pre-C region

21 January 2018

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Coinfection study of precore mutant and wild-type hepatitis B-like virus in ducklings

21 January 2018

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Mutations in the pre-core region of hepatitis B virus serve to enhance the stability of the secondary structure of the pre-genome encapsidation signal

21 January 2018

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High genomic variability in the pre-C region of hepatitis B virus in anti-HBe, HBV DNA-positive chronic hepatitis

21 January 2018

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Replication capacities of natural and artificial precore stop codon mutants of hepatitis B virus: relevance of pregenome encapsidation signal

21 January 2018

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Precore mutant of hepatitis B virus in childhood fulminant hepatitis B: an infrequent association

21 January 2018

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Differences in the entire nucleotide sequence between hepatitis B virus genomes from carriers positive for antibody to hepatitis B e antigen with and without active disease

21 January 2018

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Naturally occurring hepatitis B virus mutants with deletions in the core promoter region

21 January 2018

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Probable implication of mutations of the X open reading frame in the onset of fulminant hepatitis B.

21 January 2018

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Reduced precore transcription and enhanced core-pregenome transcription of hepatitis B virus DNA after replacement of the precore-core promoter with sequences associated with e antigen-seronegative persistent infections.

21 January 2018

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Reduced antigen production by hepatitis B virus harbouring nucleotide deletions in the overlapping X gene and precore-core promoter

21 January 2018

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Hepatitis B virus strains with mutations in the core promoter in patients with fulminant hepatitis

21 January 2018

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Hepatitis B virus core promoter sequence analysis in fulminant and chronic hepatitis B.

21 January 2018

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Mutations in the core promoter region of hepatitis B virus in patients with chronic hepatitis B.

21 January 2018

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Changes in the prevalence of HBeAg-negative mutant hepatitis B virus during the course of chronic hepatitis B.

21 January 2018

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Prevalence of precore‐defective mutant of hepatitis B virus in HBV carriers

21 January 2018

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Hepatitis B virus precore mutants are identical in carriers from various ethnic origins and are associated with a range of liver disease severity

21 January 2018

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Detection of precore hepatitis B virus mutants in asymptomatic HBsAg-positive family members

21 January 2018

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The role of pre-core hepatitis B virus mutants on the long-term outcome of chronic hepatitis B virus hepatitis. A longitudinal study

21 January 2018

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Low frequency of precore hepatitis B virus mutants in anti-hepatitis B e-positive reactivation after loss of hepatitis B e antigen in patients with chronic hepatitis B.

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Selection for a pre-C stop codon mutation in a hepatitis B virus variant with a pre-C initiation codon mutation during interferon treatment

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Frequent and rapid emergence of mutated pre-C sequences in HBV from e-antigen positive carriers who seroconvert to anti-HBe during interferon treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Genomic variations in the hepatitis B core gene: a possible factor influencing response to interferon alfa treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

HLA class I-restricted human cytotoxic T cells recognize endogenously synthesized hepatitis B virus nucleocapsid antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Reactivation of precore mutant hepatitis B virus leading to fulminant hepatic failure following cytotoxic treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Completely or nearly identical hepatitis B virus strains replicate between patients with acute or fulminant hepatitis B and their respective infectious sources

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Association of a precore genomic variant of hepatitis B virus with fulminant hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Association of hepatitis B viral precore mutations with fulminant hepatitis B in Japan

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Detection of precore/core-mutant hepatitis B virus genome in patients with acute or fulminant hepatitis without serological markers for recent HBV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Hepatitis B virus precore mutation and fulminant hepatitis in the United States. A polymerase chain reaction-based assay for the detection of specific mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Selection of a precore mutant after vertical transmission of different hepatitis B virus variants is correlated with fulminant hepatitis in infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Whole genome analysis of hepatitis B virus from four cases of fulminant hepatitis: genetic variability and its potential role in disease pathogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

A hepatitis B virus mutant with a new hepatocyte nuclear factor 1 binding site emerging in transplant-transmitted fulminant hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Hepatitis B virus genomes of patients with fulminant hepatitis do not share a specific mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Complete nucleotide sequences of hepatitis B virus genomes associated with epidemic fulminant hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Hepatitis B virus precore mutant infection is associated with severe recurrent disease after liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

A pretransplant infection with precore mutants of hepatitis B virus does not influence the outcome of orthotopic liver transplantation in patients on high dose anti-hepatitis B virus surface antigen immunoprophylaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

HLA-A31- and HLA-Aw68-restricted cytotoxic T cell responses to a single hepatitis B virus nucleocapsid epitope during acute viral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

T cell recognition of hepatitis B and C viral antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Detection of pre-C and core region mutants of hepatitis B virus in chronic hepatitis B virus carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Variations in codons 84-101 in the core nucleotide sequence correlate with hepatocellular injury in chronic hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Precore mutations and core clustering mutations in chronic hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

High degree of conservation in the hepatitis B virus core gene during the immune tolerant phase in perinatally acquired chronic hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Hepatitis B virus core protein mutations are concentrated in B cell epitopes in progressive disease and in T helper cell epitopes during clinical remission

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Concentrating missense mutations in core gene of hepatitis B virus. Evidence for adaptive mutation in chronic hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Specific deletions in the hepatitis B virus core open reading frame in patients with chronic active hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Hepatitis B virus variants with core gene deletions in the evolution of chronic hepatitis B infection

21 January 2018

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Use of dominant negative mutants of the hepadnaviral core protein as antiviral agents.

21 January 2018

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Alternative splicing of hepatitis B virus RNAs in HepG2 cells transfected with the viral DNA.

21 January 2018

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Hemodynamic and renal effects of ascites apheresis, concentration and reinfusion in advanced cirrhosis.

21 January 2018

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Antiviral agents in hepatitis B virus transfected cell lines: inhibitory and cytotoxic effect related to time of treatment

21 January 2018

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Mechanism of inhibition of duck hepatitis B virus polymerase by (-)-beta-L-2',3'-dideoxy-3'-thiacytidine

21 January 2018

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Pharmacokinetics of famciclovir in subjects with chronic hepatic disease.

21 January 2018

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Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase

21 January 2018

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Selection of mutations in the hepatitis B virus polymerase during therapy of transplant recipients with lamivudine

21 January 2018

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Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective

21 January 2018

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Defects in the precore region of the HBV genome in patients with chronic hepatitis B after sustained seroconversion from HBeAg to anti-HBe induced spontaneously or with interferon therapy

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Fulminant hepatitis related to transmission of hepatitis B variants with precore mutations between spouses

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2362.1998.00346.X

Mutation rate of the hepadnavirus genome

21 January 2018

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10.1046/J.1365-2362.1998.00346.X

21 January 2018

Identifiers

DOI

1 reference

15 December 2017

1 reference

15 December 2017