(Q45855502)

17 December 2017

title

A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration (English)

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17 December 2017

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Christine L Le Maitre

series ordinal

1

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17 December 2017

Anthony J. Freemont

series ordinal

2

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17 December 2017

author name string

Judith A Hoyland

series ordinal

3

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17 December 2017

publication date

1 February 2006

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17 December 2017

International Journal of Experimental Pathology

published in

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17 December 2017

volume

87

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17 December 2017

issue

1

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17 December 2017

page(s)

17-28

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17 December 2017

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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In vivo bioluminescent imaging of virus-mediated gene transfer and transduced cell transplantation in the intervertebral disc

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Gene Transfer of the Catabolic Inhibitor TIMP-1 Increases Measured Proteoglycans in Cells from Degenerated Human Intervertebral Discs

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Potential use of Sox9 gene therapy for intervertebral degenerative disc disease

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Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway

26 August 2018

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A potential role for cell-based therapeutics in the treatment of intervertebral disc herniation

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26 August 2018

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Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs

26 August 2018

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Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy.

26 August 2018

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Adenoviral gene therapy

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

26 August 2018

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Transfer of genes to intervertebral disc cells: proposal for a treatment strategy of spinal disorders by local gene therapy

26 August 2018

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Interleukin-1 receptor antagonist gene therapy for arthritis

26 August 2018

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Quantitative analysis of transgene protein, mRNA, and vector DNA following injection of an adenoviral vector harboring glial cell line-derived neurotrophic factor into the primate caudate nucleus

26 August 2018

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Molecular biology of degenerative disc disease

26 August 2018

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26 August 2018

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Human intervertebral disc cells are genetically modifiable by adenovirus-mediated gene transfer: implications for the clinical management of intervertebral disc disorders

26 August 2018

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26 August 2018

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Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy: an in vivo study of adenovirus-mediated transfer of the human transforming growth factor beta 1 encoding gene

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Analysis of aging and degeneration of the human intervertebral disc. Comparison of surgical specimens with normal controls.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Transfer of genes to chondrocytic cells of the lumbar spine. Proposal for a treatment strategy of spinal disorders by local gene therapy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Human IL-1Ra gene transfer into human synovial fibroblasts is chondroprotective.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Construction of adenovirus vectors through Cre-lox recombination

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Pathways to gene therapy in rheumatoid arthritis

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Gene transfer using replication-defective retroviral and adenoviral vectors

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Inflammatory cytokines in the herniated disc of the lumbar spine

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Packaging capacity and stability of human adenovirus type 5 vectors.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

The interleukin-1 receptor antagonist and its delivery by gene transfer.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Nutrition of the intervertebral disc: solute transport and metabolism

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Human intervertebral disc: structure and function

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517345

Nucleus pulposus allograft retards intervertebral disc degeneration

26 August 2018

1 reference

12 December 2020

Sensitivity of Anulus Fibrosus Cells to Interleukin 1β

1 reference

12 December 2020

Adenovirus-mediated TGF-beta(1) gene transfer to human degenerative lumbar intervertebral disc cells

1 reference

12 December 2020

Osteogenic protein-1 enhances matrix replenishment by intervertebral disc cells previously exposed to interleukin-1

1 reference

12 December 2020

Changes with age in proteoglycan synthesis in cells cultured in vitro from the inner and outer rabbit annulus fibrosus. Responses to interleukin-1 and interleukin-1 receptor antagonist protein

1 reference

12 December 2020

Low back pain in relation to lumbar disc degeneration

1 reference

12 December 2020

Matrix Metalloproteinases And Aggrecanase

1 reference

12 December 2020

Spinal biomechanics and aging are major determinants of the proteoglycan metabolism of intervertebral disc cells

1 reference

12 December 2020

Reinsertion of stimulated nucleus pulposus cells retards intervertebral disc degeneration: an in vitro and in vivo experimental study

1 reference

12 December 2020

Role of interleukin-1 in induction of matrix metalloproteinases synthesized by rat temporomandibular joint chondrocytes and disc cells

1 reference

12 December 2020

Induction of matrix metalloproteinase-2 and -3 activity in ovine nucleus pulposus cells grown in three-dimensional agarose gel culture by interleukin-1beta: a potential pathway of disc degeneration

1 reference

12 December 2020

Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc

1 reference

12 December 2020

The role of interleukin-1 on proteoglycan metabolism of rabbit annulus fibrosus cells cultured in vitro

1 reference

12 December 2020

Immunohistologic study of the ruptured intervertebral disc of the lumbar spine

1 reference

12 December 2020

Percutaneous reinsertion of the nucleus pulposus. An experimental study

1 reference

12 December 2020

Adenovirus-mediated gene transfer to nucleus pulposus cells. Implications for the treatment of intervertebral disc degeneration

1 reference

12 December 2020

10.1111/J.0959-9673.2006.00449.X

Identifiers

DOI

1 reference

17 December 2017

PMC publication ID

2517345

0 references

1 reference

17 December 2017