(Q45857163)

17 December 2017

title

Spliceosome-mediated RNA trans-splicing as a tool for gene therapy (English)

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17 December 2017

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Puttaraju M

1

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17 December 2017

Jamison SF

2

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17 December 2017

Mansfield SG

3

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17 December 2017

Garcia-Blanco MA

4

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17 December 2017

Mitchell LG

5

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17 December 2017

publication date

1 March 1999

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17 December 2017

published in

Nature Biotechnology

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17 December 2017

volume

17

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17 December 2017

issue

3

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17 December 2017

page(s)

246-252

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/6986

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cites work

The structure and function of proteins involved in mammalian pre-mRNA splicing

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Mechanical devices of the spliceosome: motors, clocks, springs, and things

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Identification of a novel Y branch structure as an intermediate in trypanosome mRNA processing: evidence for trans splicing

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Evidence for trans splicing in trypanosomes

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A trans-spliced leader sequence on actin mRNA in C. elegans.

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A spliced leader is present on a subset of mRNAs from the human parasite Schistosoma mansoni

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RNA trans-splicing in flatworms. Analysis of trans-spliced mRNAs and genes in the human parasite, Schistosoma mansoni

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Evolution of trans-splicing plant mitochondrial introns in pre-Permian times

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Discontinuous transcription and splicing in trypanosomes

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Gene expression in Leishmania: analysis of essential 5' DNA sequences

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Immunoglobulin double-isotype expression by trans-mRNA in a human immunoglobulin transgenic mouse

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A potential splicing factor is encoded by the opposite strand of the trans-spliced c-myb exon

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7 January 2021

Trans splicing of mRNA precursors in vitro

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7 January 2021

Trans splicing of mRNA precursors

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7 January 2021

The 5' and 3' splice sites come together via a three dimensional diffusion mechanism

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A two-step mechanism for 5' and 3' splice-site pairing

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Spliced leader RNAs from lower eukaryotes are trans-spliced in mammalian cells

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Natural trans-splicing in carnitine octanoyltransferase pre-mRNAs in rat liver

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Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing

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Tagging ribozyme reaction sites to follow trans-splicing in mammalian cells

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Ribozyme-mediated trans-splicing of a trinucleotide repeat.

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Ribozyme-mediated repair of sickle beta-globin mRNAs in erythrocyte precursors

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Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides

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Only three of the seven human chorionic gonadotropin beta subunit genes can be expressed in the placenta

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Human chorionic gonadotropin-beta subunit gene expression in cultured human fetal and cancer cells of different types and origins.

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Detection of metastatic breast cancer by beta-hCG polymerase chain reaction

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Isolation and characterization of human pituitary chorionic gonadotropin.

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Eutopic production of human chorionic gonadotropin beta (hCG beta) and luteinizing hormone beta (hLH beta) in the human testis

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Affinity generation of single-stranded DNA for dideoxy sequencing following the polymerase chain reaction

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Splice junctions, branch point sites, and exons: sequence statistics, identification, and applications to genome project

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Classification of introns: U2-type or U12-type

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Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA

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The role of the mammalian branchpoint sequence in pre-mRNA splicing

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The organization of 3' splice-site sequences in mammalian introns

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Identifiers

DOI

10.1038/6986

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17 December 2017

Dimensions Publication ID

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17 December 2017