(Q45858420)

English

Dendritic cells genetically engineered to express IL-4 exhibit enhanced IL-12p70 production in response to CD40 ligation and accelerate organ allograft rejection

scientific article published in January 2003

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scholarly article

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

Dendritic cells genetically engineered to express IL-4 exhibit enhanced IL-12p70 production in response to CD40 ligation and accelerate organ allograft rejection (English)

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

1 reference

based on heuristic

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author name string

Kaneko K

1

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

Wang Z

2

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

Kim SH

3

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

Morelli AE

4

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

Robbins PD

5

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

Thomson AW

6

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

publication date

1 January 2003

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

10

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

143-152

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

2

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

https://scigraph.springernature.com/pub.10.1038/sj.gt.3301872

0 references

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Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection

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Bone marrow-derived dendritic cell progenitors (NLDC 145+, MHC class II+, B7-1dim, B7-2-) induce alloantigen-specific hyporesponsiveness in murine T lymphocytes

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Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80dim, CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients

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Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo

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Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells

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Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells

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Designer dendritic cells for tolerance induction: guided not misguided missiles

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Potential of tolerogenic dendritic cells for transplantation

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Adenoviral delivery of CTLA4Ig into myeloid dendritic cells promotes their in vitro tolerogenicity and survival in allogeneic recipients

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Feasibility of CTLA4Ig gene delivery and expression in vivo using retrovirally transduced myeloid dendritic cells that induce alloantigen-specific T cell anergy in vitro

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Induction of antigen-specific immunosuppression by CD95L cDNA-transfected 'killer' dendritic cells

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Phenotype, function, and in vivo migration and survival of allogeneic dendritic cell progenitors genetically engineered to express TGF-beta

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Human myeloid dendritic cells transduced with an adenoviral interleukin-10 gene construct inhibit human skin graft rejection in humanized NOD-scid chimeric mice

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A dendritic cell line genetically modified to express CTLA4-IG as a means to prolong islet allograft survival

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Murine interleukin 4 transgenic heart allograft survival prolonged with down-regulation of the Th1 cytokine mRNA in grafts.

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Adenovirus-mediated gene transfer of IL-4 prolongs rat renal allograft survival and inhibits the p21(ras)-activation pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

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Heart transplants in interferon-gamma, interleukin 4, and interleukin 10 knockout mice. Recipient environment alters graft rejection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

21 January 2018

Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

21 January 2018

Recombinant adenovirus induces maturation of dendritic cells via an NF-kappaB-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

21 January 2018

Interleukin-10 produced by recombinant adenovirus prolongs survival of cardiac allografts in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

21 January 2018

Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

21 January 2018

CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal

1 reference

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21 January 2018

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

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21 January 2018

Genetic engineering of dendritic cells to express immunosuppressive molecules (viral IL-10, TGF-beta, and CTLA4Ig).

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

7 January 2021

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Transduction of dendritic cell progenitors with a retroviral vector encoding viral interleukin-10 and enhanced green fluorescent protein allows purification of potentially tolerogenic antigen-presenting cells

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

7 January 2021

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Synergy in induction of increased renal allograft survival after portal vein infusion of dendritic cells transduced to express TGFbeta and IL-10, along with administration of CHO cells expressing the regulatory molecule OX-2

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7 January 2021

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Dendritic cells genetically engineered to express Fas ligand induce donor-specific hyporesponsiveness and prolong allograft survival

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Administration of intragraft interleukin-4 prolongs cardiac allograft survival in rats treated with donor-specific transfusion/cyclosporine

1 reference

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7 January 2021

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Treatment with interleukin-4 prolongs allogeneic neonatal heart graft survival by inducing T helper 2 responses

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7 January 2021

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Combination therapy with cyclosporine and interleukin-4 or interleukin-10 prolongs survival of synergeneic pancreatic islet grafts in nonobese diabetic mice: islet graft survival does not correlate with mRNA levels of type 1 or type 2 cytokines, or

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

7 January 2021

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Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

7 January 2021

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Operational tolerance induced by pretreatment with donor dendritic cells under blockade of CD40 pathway

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7 January 2021

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Blockade of the CD40-CD40 ligand pathway potentiates the capacity of donor-derived dendritic cell progenitors to induce long-term cardiac allograft survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

7 January 2021

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IL-4 Is a Mediator of IL-12p70 Induction by Human Th2 Cells: Reversal of Polarized Th2 Phenotype by Dendritic Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

7 January 2021

based on heuristic

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CD40L-induced IL-12 production is further enhanced by the Th2 cytokines IL-4 and IL-13

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301872

7 January 2021

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Contrasting effects of myeloid dendritic cells transduced with an adenoviral vector encoding interleukin-10 on organ allograft and tumour rejection

1 reference

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7 January 2021

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inferred from DOI database lookup

Identifiers

10.1038/SJ.GT.3301872

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

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0 references

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/12571643

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