(Q45859175)

17 December 2017

title

Induction of the p16INK4a senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis (English)

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17 December 2017

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Taniguchi K

1

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17 December 2017

Kohsaka H

2

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17 December 2017

Inoue N

3

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17 December 2017

Terada Y

4

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17 December 2017

Ito H

5

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17 December 2017

Hirokawa K

6

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17 December 2017

Miyasaka N

7

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17 December 2017

language of work or name

English

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publication date

1 July 1999

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17 December 2017

published in

Nature Medicine

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17 December 2017

volume

5

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17 December 2017

issue

7

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17 December 2017

page(s)

760-767

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/10480

exact match

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cites work

The role of T cells in the immunopathogenesis of rheumatoid arthritis: new perspectives

1 reference

The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

21 January 2018

1 reference

Monoclonal anti‐TNFα Antibody as a Probe of Pathogenesis and Therapy of Rheumatoid Disease

21 January 2018

1 reference

Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects

21 January 2018

1 reference

Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee

21 January 2018

1 reference

Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer.

21 January 2018

1 reference

Suppression of collagen-induced arthritis through adenovirus-mediated transfer of a modified tumor necrosis factor alpha receptor gene.

21 January 2018

1 reference

Plasmid DNA encoding transforming growth factor-beta1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model

21 January 2018

1 reference

Apoptosis in rheumatoid arthritis synovium

21 January 2018

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Inhibitors of mammalian G1 cyclin-dependent kinases

21 January 2018

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Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

21 January 2018

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Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

21 January 2018

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Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

21 January 2018

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p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 January 2018

1 reference

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

21 January 2018

1 reference

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

21 January 2018

1 reference

p21 is a universal inhibitor of cyclin kinases

21 January 2018

1 reference

Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death

21 January 2018

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Adenoviral-mediated gene transfer to rabbit synovium in vivo.

21 January 2018

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Features of replicative senescence induced by direct addition of antennapedia-p16INK4A fusion protein to human diploid fibroblasts

21 January 2018

1 reference

Induction of senescence in human malignant glioma cells by p16INK4A.

21 January 2018

1 reference

A cell cycle regulator potentially involved in genesis of many tumor types

21 January 2018

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Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

21 January 2018

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Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

21 January 2018

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Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts

21 January 2018

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Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells.

21 January 2018

1 reference

Integrin alpha v beta 5 selectively promotes adenovirus mediated cell membrane permeabilization.

21 January 2018

1 reference

Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

21 January 2018

1 reference

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

21 January 2018

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Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase

21 January 2018

1 reference

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

21 January 2018

1 reference

Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein

21 January 2018

1 reference

7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

7 January 2021

Rates of p16 (MTS1) mutations in primary tumors with 9p loss

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7 January 2021

Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery

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7 January 2021

Fractionated total lymphoid irradiation: a promising new treatment for rheumatoid arthritis? Yes, no, maybe

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7 January 2021

Identifiers

DOI

10.1038/10480

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17 December 2017

Dimensions Publication ID

1030380784

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17 December 2017