(Q45859857)

17 December 2017

title

Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders (English)

1 reference

17 December 2017

main subject

autism spectrum disorder

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9

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17 December 2017

author name string

Stefanie Grabrucker

1

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17 December 2017

Linda Jannetti

2

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17 December 2017

Matti Eckert

3

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17 December 2017

Simone Gaub

4

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17 December 2017

Resham Chhabra

5

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17 December 2017

Stefanie Pfaender

6

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17 December 2017

Katharina Mangus

7

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17 December 2017

Parameshwar Pasham Reddy

8

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17 December 2017

Michael J Schmeisser

10

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17 December 2017

Michael R Kreutz

11

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17 December 2017

Günter Ehret

12

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17 December 2017

Tobias M Boeckers

13

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17 December 2017

Andreas M Grabrucker

14

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17 December 2017

language of work or name

English

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publication date

25 November 2013

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17 December 2017

published in

Brain

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17 December 2017

volume

137

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17 December 2017

issue

Pt 1

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17 December 2017

page(s)

137-152

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17 December 2017

Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autism

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1 reference

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An architectural framework that may lie at the core of the postsynaptic density

21 January 2018

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Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

21 January 2018

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Zinc: the brain's dark horse.

21 January 2018

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Disruption of the ProSAP2 gene in a t(12;22)(q24.1;q13.3) is associated with the 22q13.3 deletion syndrome

21 January 2018

1 reference

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Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene

21 January 2018

1 reference

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Measurement of zinc in hepatocytes by using a fluorescent probe, zinquin: relationship to metallothionein and intracellular zinc

21 January 2018

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Nitric oxide generators produce accumulation of chelatable zinc in hippocampal neuronal perikarya

21 January 2018

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Nutritional and environmental approaches to preventing and treating autism and attention deficit hyperactivity disorder (ADHD): a review

21 January 2018

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Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

21 January 2018

1 reference

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The plasma zinc/serum copper ratio as a biomarker in children with autism spectrum disorders

21 January 2018

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The neurobiology of zinc in health and disease

21 January 2018

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Depletion of intracellular zinc from neurons by use of an extracellular chelator in vivo and in vitro

21 January 2018

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Novel de novo SHANK3 mutation in autistic patients

21 January 2018

1 reference

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Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold

21 January 2018

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Synaptogenesis of hippocampal neurons in primary cell culture

21 January 2018

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A novel non-perfusion Timm method for human brain tissue

21 January 2018

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Structural role of zinc ions bound to postsynaptic densities

21 January 2018

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Syndromes associated with nutritional deficiency and excess

21 January 2018

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Zinc-buffering capacity of a eukaryotic cell at physiological pZn.

21 January 2018

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Maternal care in house mice

21 January 2018

1 reference

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Metallothionein-3 deficient mice exhibit abnormalities of psychological behaviors

21 January 2018

1 reference

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Level of trace elements (copper, zinc, magnesium and selenium) and toxic elements (lead and mercury) in the hair and nail of children with autism.

21 January 2018

1 reference

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Sensory overresponsivity and anxiety in typically developing children and children with autism and attention deficit hyperactivity disorder: cause or coexistence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Zinc released from metallothionein-iii may contribute to hippocampal CA1 and thalamic neuronal death following acute brain injury

21 January 2018

1 reference

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Release of intracellular Zn(2+) in cultured neurons after brief exposure to low concentrations of exogenous nitric oxide.

21 January 2018

1 reference

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Terminal 22q deletion syndrome: a newly recognized cause of speech and language disability in the autism spectrum

21 January 2018

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Contribution of SHANK3 mutations to autism spectrum disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

21 January 2018

22q13 deletion syndrome

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Functional impact of global rare copy number variation in autism spectrum disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Reference values for the trace elements copper, manganese, selenium, and zinc in the serum/plasma of children, adolescents, and adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Analysis of Copper and Zinc Plasma Concentration and the Efficacy of Zinc Therapy in Individuals with Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) and Autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Zinc deficiency: Effects on brain and behavior of rats and Rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

SHANK1 Deletions in Males with Autism Spectrum Disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Local sharing as a predominant determinant of synaptic matrix molecular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

The effect of nitric oxide on metal release from metallothionein-3: gradual unfolding of the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Characterization of extracellular accumulation of Zn2+ during ischemia and reperfusion of hippocampus slices in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

Infantile zinc deficiency: association with autism spectrum disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT303

21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWT303

1 reference

17 December 2017

1 reference

17 December 2017