(Q45861365)

English

Adoptive immunotherapy with genetically engineered T cells: modification of the IgG1 Fc 'spacer' domain in the extracellular moiety of chimeric antigen receptors avoids 'off-target' activation and unintended initiation of an innate immune response

scientific article published on 17 June 2010

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

Adoptive immunotherapy with genetically engineered T cells: modification of the IgG1 Fc 'spacer' domain in the extracellular moiety of chimeric antigen receptors avoids 'off-target' activation and unintended initiation of an innate immune response (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

1 reference

based on heuristic

inferred from title

author name string

A Hombach

1

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

A A Hombach

2

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

H Abken

3

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

publication date

17 June 2010

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

17

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

10

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

1206-1213

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

https://scigraph.springernature.com/pub.10.1038/gt.2010.91

0 references

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

Noninvasive detection of therapeutic cytolytic T cells with 18F-FHBG PET in a patient with glioma

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

Immune response manipulation: recombinant immunoreceptors endow T-cells with predefined specificity

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

Differential binding to human FcgammaRIIa and FcgammaRIIb receptors by human IgG wildtype and mutant antibodies.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

Recombinant human IgG molecules lacking Fcgamma receptor I binding and monocyte triggering activities

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

Genetic engineering of cytolytic T lymphocytes for adoptive T-cell therapy of neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

Increased intensity lymphodepletion and adoptive immunotherapy--how far can we go?

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

A retroviral vector system 'STITCH' in combination with an optimized single chain antibody chimeric receptor gene structure allows efficient gene transduction and expression in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

Functional balance between T cell chimeric receptor density and tumor associated antigen density: CTL mediated cytolysis and lymphokine production

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

21 January 2018

Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

7 January 2021

based on heuristic

inferred from DOI database lookup

The T-body approach: redirecting T cells with antibody specificity

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of extracellular spacer regions in the optimal design of chimeric immune receptors: evaluation of four different scFvs and antigens

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

7 January 2021

based on heuristic

inferred from DOI database lookup

Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

7 January 2021

based on heuristic

inferred from DOI database lookup

Monoclonal anti-idiotype antibody 6G6.C4 fused to GM-CSF is capable of breaking tolerance to carcinoembryonic antigen (CEA) in CEA-transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

7 January 2021

based on heuristic

inferred from DOI database lookup

CD30-specific AB1-AB2-AB3 internal image antibody network: potential use as anti-idiotype vaccine against Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

7 January 2021

based on heuristic

inferred from DOI database lookup

Improved short- and long-term XTT-based colorimetric cellular cytotoxicity assay for melanoma and other tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2010.91

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/GT.2010.91

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/20555360

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q45861365&oldid=2086786236"