(Q45861565)

English

Augmentation of natural immunity to a pro-inflammatory cytokine (TNF-alpha) by targeted DNA vaccine confers long-lasting resistance to experimental autoimmune encephalomyelitis

scientific article published in June 1999

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10455416

Augmentation of natural immunity to a pro-inflammatory cytokine (TNF-alpha) by targeted DNA vaccine confers long-lasting resistance to experimental autoimmune encephalomyelitis (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10455416

author name string

Wildbaum G

1

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10455416

Karin N

2

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10455416

publication date

1 June 1999

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10455416

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10455416

6

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10455416

6

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10455416

1128-1138

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10455416

https://scigraph.springernature.com/pub.10.1038/sj.gt.3300915

0 references

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21 January 2018

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

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Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon gamma and tumor necrosis factor alpha production

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21 January 2018

Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein

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21 January 2018

Role of cytokines in determining T-lymphocyte function

1 reference

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Functional diversity of helper T lymphocytes

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21 January 2018

Cytokine transcriptional events during helper T cell subset differentiation

1 reference

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Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming

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21 January 2018

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

1 reference

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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

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The role of IL-10 in crossregulation of TH1 and TH2 responses

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21 January 2018

Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease

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B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

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21 January 2018

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

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21 January 2018

In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice

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Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype

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21 January 2018

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

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21 January 2018

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

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https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

21 January 2018

Interleukin-10 prevents experimental allergic encephalomyelitis in rats.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

21 January 2018

Interleukin-12 and its role in the generation of TH1 cells

1 reference

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21 January 2018

TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination.

1 reference

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21 January 2018

Human tumor necrosis factor-alpha augments experimental allergic encephalomyelitis in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

21 January 2018

An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis

1 reference

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21 January 2018

Anti?tumor necrosis factor therapy abrogates autoimmune demyelination

1 reference

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21 January 2018

Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting

1 reference

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21 January 2018

Challenging cytokine redundancy: inflammatory cell movement and clinical course of experimental autoimmune encephalomyelitis are normal in lymphotoxin-deficient, but not tumor necrosis factor-deficient, mice

1 reference

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21 January 2018

A critical role for lymphotoxin in experimental allergic encephalomyelitis

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21 January 2018

Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis.

1 reference

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21 January 2018

Soluble tumor necrosis factor receptor inhibits interleukin 12 production by stimulated human adult microglial cells in vitro

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From antilymphocyte serum to therapeutic monoclonal antibodies: first experiences with a chimeric CD4 antibody in the treatment of autoimmune disease

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Protection against mycoplasma infection using expression-library immunization

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Genetic immunization is a simple method for eliciting an immune response

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Heterologous protection against influenza by injection of DNA encoding a viral protein

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Immunostimulatory DNA sequences necessary for effective intradermal gene immunization

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T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus

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T cell determinants of myelin basic protein include a unique encephalitogenic I-E-restricted epitope for Lewis rats.

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Myelin basic protein‐specific T lymphocyte lines from MS patients and healthy individuals

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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

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Induction of anergy or active suppression following oral tolerance is determined by antigen dosage.

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An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

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Escape from "horror autotoxicus": pathogenesis and treatment of autoimmune disease

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Tolerance, danger, and the extended family

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The immune system evolved to discriminate infectious nonself from noninfectious self

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Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

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Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination.

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Systemic immunological effects of cytokine genes injected into skeletal muscle

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Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization

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Vaccination against tuberculosis by DNA injection

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Plasmid DNA encoding transforming growth factor-beta1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model

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Experimental allergic encephalomyelitis: neutralizing antibody to TGF beta 1 enhances the clinical severity of the disease.

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Reversal of acute and chronic synovial inflammation by anti-transforming growth factor beta

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Modulation of disease activity in murine systemic lupus erythematosus by cytokine gene delivery

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Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection.

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21 January 2018

Antigen-induced programmed T cell death as a new approach to immune therapy

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Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs

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TH2 activated cells prevent experimental autoimmune uveoretinitis, a TH1-dependent autoimmune disease

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T cell tolerance by clonal elimination in the thymus

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21 January 2018

Chemokine expression in murine experimental allergic encephalomyelitis

1 reference

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21 January 2018

Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β

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https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

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https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

7 January 2021

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Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity

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https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

7 January 2021

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Tumor necrosis factor blockade in actively induced experimental autoimmune encephalomyelitis prevents clinical disease despite activated T cell infiltration to the central nervous system

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https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

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Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-alpha in the central nervous system

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https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

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https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

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https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

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Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity

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https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

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Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4,

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https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

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https://api.crossref.org/works/10.1038%2FSJ.GT.3300915

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Identifiers

10.1038/SJ.GT.3300915

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10455416

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10455416

ResearchGate publication ID

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