(Q45862963)

17 December 2017

title

Potent antitumor activity of IL-13 cytotoxin in human pancreatic tumors engineered to express IL-13 receptor alpha2 chain in vivo (English)

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17 December 2017

author name string

Kawakami K

1

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17 December 2017

Kawakami M

2

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17 December 2017

Husain SR

3

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17 December 2017

Puri RK

4

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17 December 2017

publication date

1 July 2003

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

10

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17 December 2017

issue

13

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17 December 2017

page(s)

1116-1128

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.gt.3301956

exact match

0 references

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Superantigen-based immunotherapy: a phase I trial of PNU-214565, a monoclonal antibody-staphylococcal enterotoxin A recombinant fusion protein, in advanced pancreatic and colorectal cancer

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Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial

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Microencapsulated cell-mediated treatment of inoperable pancreatic carcinoma.

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Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses

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Experimental gene therapy of cancer using tumor cells engineered to secrete interleukin-13.

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Mutation and Functional Analysis of IL-13 Receptors in Human Malignant Glioma Cells

21 January 2018

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Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common gamma chain shared by receptors for interleukins 2, 4, 7, 9, and 15.

21 January 2018

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Human ovarian-carcinoma cell lines express IL-4 and IL-13 receptors: comparison between IL-4- and IL-13-induced signal transduction

21 January 2018

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Modulation of interleukin (IL)-13 binding and signaling by the gammac chain of the IL-2 receptor

21 January 2018

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cDNA cloning and characterization of the human interleukin 13 receptor alpha chain

21 January 2018

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Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

21 January 2018

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Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex

21 January 2018

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The IL-4 receptor: signaling mechanisms and biologic functions

21 January 2018

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Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain

21 January 2018

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Identification of distinct roles for a dileucine and a tyrosine internalization motif in the interleukin (IL)-13 binding component IL-13 receptor alpha 2 chain

21 January 2018

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Structure of IL-13 receptor: analysis of subunit composition in cancer and immune cells

21 January 2018

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Two different IL-13 receptor chains are expressed in normal human skin fibroblasts, and IL-4 and IL-13 mediate signal transduction through a common pathway

21 January 2018

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Gene transfer of interleukin 13 receptor alpha2 chain dramatically enhances the antitumor effect of IL-13 receptor-targeted cytotoxin in human prostate cancer xenografts

21 January 2018

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Interleukin-13 receptor as a unique target for anti-glioblastoma therapy

21 January 2018

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In vivo overexpression of IL-13 receptor alpha2 chain inhibits tumorigenicity of human breast and pancreatic tumors in immunodeficient mice

21 January 2018

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Apoptotic pathways of cell death induced by an interleukin-13 receptor-targeted recombinant cytotoxin in head and neck cancer cells

21 January 2018

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Conversion of interleukin-13 into a high affinity agonist by a single amino acid substitution

21 January 2018

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Immunogenicity and protective efficacy of a Plasmodium yoelii Hsp60 DNA vaccine in BALB/c mice

21 January 2018

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Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin-4.

21 January 2018

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Improved DNA: liposome complexes for increased systemic delivery and gene expression

21 January 2018

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The interleukin-13 receptor alpha2 chain: an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301956

7 January 2021

Human breast carcinoma cells express type II IL-4 receptors and are sensitive to antitumor activity of a chimeric IL-4-Pseudomonas exotoxin fusion protein in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301956

7 January 2021

A novel chimeric protein composed of interleukin 13 and Pseudomonas exotoxin is highly cytotoxic to human carcinoma cells expressing receptors for interleukin 13 and interleukin 4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301956

7 January 2021

Sensitization of cancer cells to interleukin 13-pseudomonas exotoxin-induced cell death by gene transfer of interleukin 13 receptor alpha chain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301956

7 January 2021

In vitro and in vivo suppression of interleukin-2-activated killer cell activity by chimeric proteins between interleukin-2 and Pseudomonas exotoxin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301956

7 January 2021

NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301956

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301956

1 reference

17 December 2017

Dimensions Publication ID

1023738697

0 references

1 reference

17 December 2017