(Q45863741)

English

Engineered RNase P ribozymes are efficient in cleaving a human cytomegalovirus mRNA in vitro and are effective in inhibiting viral gene expression and growth in human cells

scientific article published on 15 July 2003

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

Engineered RNase P ribozymes are efficient in cleaving a human cytomegalovirus mRNA in vitro and are effective in inhibiting viral gene expression and growth in human cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

Cytomegalovirus

0 references

2

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

author name string

Hua Zou

1

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

Sean Umamoto

3

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

Ahmed F Kilani

4

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

Joseph Kim

5

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

Phong Trang

6

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

Tianhong Zhou

7

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

Fenyong Liu

8

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

language of work or name

0 references

publication date

15 July 2003

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

278

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

39

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

37265-37274

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

Ribozymes, genomics and therapeutics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

A controlled, Phase 1 clinical trial to evaluate the safety and effects in HIV-1 infected humans of autologous lymphocytes transduced with a ribozyme that cleaves HIV-1 RNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

A hairpin ribozyme inhibits expression of diverse strains of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Ribozymes as potential anti-HIV-1 therapeutic agents.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Ribozyme-mediated repair of sickle beta-globin mRNAs in erythrocyte precursors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Ribonuclease P: unity and diversity in a tRNA processing ribozyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Further perspective on the catalytic core and secondary structure of ribonuclease P RNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Evolutionary variation in bacterial RNase P RNAs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Molecular modeling of the three-dimensional structure of the bacterial RNase P holoenzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Crystal structure of the specificity domain of ribonuclease P

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Derivation of the three-dimensional architecture of bacterial ribonuclease P RNAs from comparative sequence analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Comparative photocross-linking analysis of the tertiary structures of Escherichia coli and Bacillus subtilis RNase P RNAs.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

External Guide Sequences for an RNA Enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Model substrates for an RNA enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Inhibition of viral gene expression by the catalytic RNA subunit of RNase P from Escherichia coli.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Rational design of self-cleaving pre-tRNA-ribonuclease P RNA conjugates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Effective inhibition of human cytomegalovirus gene expression and replication by a ribozyme derived from the catalytic RNA subunit of RNase P from Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Differential effects of the protein cofactor on the interactions between an RNase P ribozyme and its target mRNA substrate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

UV cross-link mapping of the substrate-binding site of an RNase P ribozyme to a target mRNA sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

RNase P ribozymes selected in vitro to cleave a viral mRNA effectively inhibit its expression in cell culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Nuclease footprint analyses of the interactions between RNase P ribozyme and a model mRNA substrate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Lethal and temperature-sensitive mutations and their suppressors identify an essential structural element in U2 small nuclear RNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Inhibition of viral gene expression by human ribonuclease P.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Targeted cleavage of mRNA by human RNase P

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

In vitro genetics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

In vitro selection of active hairpin ribozymes by sequential RNA-catalyzed cleavage and ligation reactions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

AUA-cleaving hammerhead ribozymes: attempted selection for improved cleavage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

In vitro genetic analysis of the Tetrahymena self-splicing intron

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Kinetics of intermolecular cleavage by hammerhead ribozymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Multiple magnesium ions in the ribonuclease P reaction mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303531200

21 January 2018

Identifiers

10.1074/JBC.M303531200

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/12867424

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q45863741&oldid=2086826403"