(Q45864839)

17 December 2017

title

The adenosine A2A receptor agonist CGS 21680 decreases ethanol self-administration in both non-dependent and dependent animals (English)

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17 December 2017

main subject

CGS-21680

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ChEBI release 2020-05-28

Hakim Houchi

1

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17 December 2017

Wolfgang Persyn

series ordinal

2

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17 December 2017

Rémi Legastelois

series ordinal

3

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17 December 2017

Mickaël Naassila

series ordinal

4

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17 December 2017

language of work or name

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10 January 2013

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17 December 2017

published in

Addiction Biology

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17 December 2017

volume

18

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17 December 2017

issue

5

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17 December 2017

page(s)

812-825

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17 December 2017

Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats

cites work

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Effect of baclofen on alcohol and sucrose self-administration in rats

21 January 2018

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Ethanol operant self-administration in rats is regulated by adenosine A2 receptors

21 January 2018

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Effects of adenosine A2A receptor stimulation on cocaine-seeking behavior in rats.

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Enkephalin may mediate euphoria and drive-reduction reward

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The type 1 equilibrative nucleoside transporter regulates ethanol intoxication and preference.

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Recent developments in adenosine A2A receptor ligands

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Evidence for high-affinity binding sites for the adenosine A2A receptor agonist [3H] CGS 21680 in the rat hippocampus and cerebral cortex that are different from striatal A2A receptors

21 January 2018

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Ethanol- and sucrose-reinforced appetitive and consummatory responding in HAD1, HAD2, and P rats

21 January 2018

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Modulation of ethanol-induced motor incoordination by mouse striatal A(1) adenosinergic receptor

21 January 2018

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Effect of the cannabinoid CB1 receptor antagonist SR-141716A on ethanol self-administration and ethanol-seeking behaviour in rats

21 January 2018

1 reference

SCH 58261 and ZM 241385 differentially prevent the motor effects of CGS 21680 in mice: evidence for a functional 'atypical' adenosine A(2A) receptor.

21 January 2018

1 reference

Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry implications for drug addiction, sleep and pain

21 January 2018

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Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia

21 January 2018

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Adenosine-cannabinoid receptor interactions. Implications for striatal function

21 January 2018

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Involvement of adenosine A2A and dopamine receptors in the locomotor and sensitizing effects of cocaine

21 January 2018

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Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum

21 January 2018

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Adenosine A1 receptors modulate anxiety in CD1 mice

21 January 2018

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Intra-accumbens injections of the adenosine A2A agonist CGS 21680 affect effort-related choice behavior in rats

21 January 2018

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Aspects of the general biology of adenosine A2A signaling.

21 January 2018

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Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function

21 January 2018

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Adenosine receptor-dopamine receptor interactions in the basal ganglia and their relevance for brain function.

21 January 2018

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Endogenous opioids and addiction to alcohol and other drugs of abuse

21 January 2018

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Forebrain PENK and PDYN gene expression levels in three inbred strains of mice and their relationship to genotype-dependent morphine reward sensitivity

21 January 2018

1 reference

Pharmacogenetic approaches to the treatment of alcohol addiction

21 January 2018

1 reference

Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors

21 January 2018

1 reference

Involvement of A2A receptors in anxiolytic, locomotor and motivational properties of ethanol in mice

21 January 2018

1 reference

Endogenous BDNF in the dorsolateral striatum gates alcohol drinking

21 January 2018

1 reference

Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor

21 January 2018

1 reference

Differential effects of the adenosine A₂A agonist CGS-21680 and haloperidol on food-reinforced fixed ratio responding in the rat.

21 January 2018

1 reference

Reinforcing and neurochemical effects of cannabinoid CB1 receptor agonists, but not cocaine, are altered by an adenosine A2A receptor antagonist

21 January 2018

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Adenosine agonists CGS 21680 and NECA inhibit the initiation of cocaine self-administration

21 January 2018

1 reference

Emotional instability but intact spatial cognition in adenosine receptor 1 knock out mice

21 January 2018

1 reference

Genetics of dopamine receptors and drug addiction: a comprehensive review

21 January 2018

1 reference

Binding of the prototypical adenosine A(2A) receptor agonist CGS 21680 to the cerebral cortex of adenosine A(1) and A(2A) receptor knockout mice.

21 January 2018

1 reference

Pharmacotherapy of alcohol dependence: a review of the clinical data

21 January 2018

1 reference

Adenosine A1, but not A2, receptor blockade increases anxiety and arousal in Zebrafish.

21 January 2018

1 reference

Effects of A₂A adenosine receptor blockade or stimulation on alcohol intake in alcohol-preferring rats

21 January 2018

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Intracerebroventricular injection of antisense oligos to nNOS decreases rat ethanol intake

21 January 2018

1 reference

Adenosine A2A receptors in the nucleus accumbens bi-directionally alter cocaine seeking in rats

21 January 2018

1 reference

Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice.

21 January 2018

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Inhibition of orexin-1/hypocretin-1 receptors inhibits yohimbine-induced reinstatement of ethanol and sucrose seeking in Long-Evans rats

21 January 2018

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Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol

21 January 2018

1 reference

Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats.

21 January 2018

1 reference

Neurochemistry of the nucleus accumbens and its relevance to depression and antidepressant action in rodents

21 January 2018

1 reference

Fluoxetine, desipramine, and the dual antidepressant milnacipran reduce alcohol self-administration and/or relapse in dependent rats

21 January 2018

1 reference

Endogenous enkephalins, not endorphins, modulate basal hedonic state in mice

21 January 2018

1 reference

Role of dynorphin and enkephalin in the regulation of striatal output pathways and behavior

21 January 2018

1 reference

Distribution, biochemistry and function of striatal adenosine A2A receptors

21 January 2018

1 reference

Role of adenosine A(2A) receptors in modulating synaptic functions and brain levels of BDNF: a possible key mechanism in the pathophysiology of Huntington's disease.

21 January 2018

1 reference

Effect of the adenosine A2a receptor antagonist 3,7-dimethyl-propargylxanthine on anxiety-like and depression-like behavior and alcohol consumption in Wistar Rats

21 January 2018

1 reference

Biochemical identification of the dopamine D2 receptor domains interacting with the adenosine A2A receptor.

21 January 2018

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alpha1-noradrenergic receptor antagonism blocks dependence-induced increases in responding for ethanol

21 January 2018

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Influence of CGS 21680, a selective adenosine A(2A) agonist, on the phencyclidine-induced sensorimotor gating deficit and motor behaviour in rats

21 January 2018

1 reference

The adenosine receptor antagonist CGS15943 reinstates cocaine-seeking behavior and maintains self-administration in baboons.

21 January 2018

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Mice heterozygous for both A1 and A(2A) adenosine receptor genes show similarities to mice given long-term caffeine

21 January 2018

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Voluntary ethanol consumption in 22 inbred mouse strains

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/ADB.12032

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17 December 2017

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17 December 2017