(Q45865590)

English

Ectopic retroviral expression of LMO2, but not IL2Rgamma, blocks human T-cell development from CD34+ cells: implications for leukemogenesis in gene therapy.

scientific article published in February 2007

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scholarly article

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25 December 2019

Ectopic retroviral expression of LMO2, but not IL2Rgamma, blocks human T-cell development from CD34+ cells: implications for leukemogenesis in gene therapy (English)

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25 December 2019

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Martijn Brugman

6

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25 December 2019

Jacques Van Dongen

11

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25 December 2019

author name string

Pike-Overzet K

1

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25 December 2019

de Ridder D

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25 December 2019

Weerkamp F

3

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25 December 2019

Baert MR

4

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25 December 2019

Verstegen MM

5

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25 December 2019

Howe SJ

7

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25 December 2019

Reinders MJ

8

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25 December 2019

Thrasher AJ

9

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25 December 2019

Wagemaker G

10

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25 December 2019

Staal FJ

12

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25 December 2019

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publication date

1 February 2007

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25 December 2019

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25 December 2019

21

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25 December 2019

4

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25 December 2019

754-763

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25 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404563

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Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

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Gene therapy of X-linked severe combined immunodeficiency

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Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

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Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

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A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

1 reference

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7 January 2021

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Gene therapy. Second child in French trial is found to have leukemia

1 reference

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7 January 2021

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

1 reference

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7 January 2021

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Gene therapy insertional mutagenesis insights

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7 January 2021

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Gene therapy: therapeutic gene causing lymphoma

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Acute monoblastic leukemia of infancy in Klinefelter's syndrome

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Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

1 reference

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Is IL2RG oncogenic in T-cell development?: X-SCID transgene leukaemogenicity (reply)

1 reference

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7 January 2021

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Unique risk factors for insertional mutagenesis in a mouse model of XSCID gene therapy

1 reference

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7 January 2021

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Gene therapy: is IL2RG oncogenic in T-cell development?

1 reference

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7 January 2021

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New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.

1 reference

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7 January 2021

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Stimulation of mouse bone marrow cells with kit ligand, FLT3 ligand, and thrombopoietin leads to efficient retrovirus-mediated gene transfer to stem cells, whereas interleukin 3 and interleukin 11 reduce transduction of short- and long-term repopula

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404563

7 January 2021

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Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404563

7 January 2021

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Exploration, normalization, and summaries of high density oligonucleotide array probe level data

1 reference

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7 January 2021

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A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

1 reference

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7 January 2021

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Maximum significance clustering of oligonucleotide microarrays.

1 reference

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Episomal vectors rapidly and stably produce high-titer recombinant retrovirus

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7 January 2021

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Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potential.

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Gene-expression profiling of CD34+ cells from various hematopoietic stem-cell sources reveals functional differences in stem-cell activity

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1 reference

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1 reference

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1 reference

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1 reference

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7 January 2021

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1 reference

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1 reference

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1 reference

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Identifiers

10.1038/SJ.LEU.2404563

1 reference

Europe PubMed Central

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25 December 2019

Dimensions Publication ID

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1 reference

Europe PubMed Central

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25 December 2019

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