(Q45867029)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Phase I/II trial of a dendritic cell vaccine transfected with DNA encoding melan A and gp100 for patients with metastatic melanoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

main subject

phase II clinical trial

0 references

phase I clinical trial

0 references

1 reference

1 reference

Lucinda J. Billingham

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Lawrence S Young

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

J C Steele

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

A Rao

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

J R Marsden

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

C J Armstrong

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

S Berhane

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

N Graham

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

C Roberts

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

G Ryan

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

H Uppal

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

C Walker

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

N M Steven

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

publication date

10 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

584-593

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21307889%20AND%20SRC:MED&resulttype=core&format=json

Dendritic cell subsets in health and disease.

22 January 2020

cites work

1 reference

21 January 2018

DC-based cancer vaccines

1 reference

Synthetic DNA delivery systems

21 January 2018

1 reference

Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells

21 January 2018

1 reference

Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA.

21 January 2018

1 reference

Immunotherapy with Autologous, Human Dendritic Cells Transfected with Carcinoembryonic Antigen mRNA

21 January 2018

1 reference

Induction of Tumor-Specific Cytotoxic T Lymphocytes in Cancer Patients by Autologous Tumor RNA-Transfected Dendritic Cells

21 January 2018

1 reference

Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors

21 January 2018

1 reference

CL22 - a novel cationic peptide for efficient transfection of mammalian cells

21 January 2018

1 reference

Long-Term Human B Cell Lines Dependent on Interleukin-4 and antibody to CD40

21 January 2018

1 reference

Directed evolution of human T-cell receptors with picomolar affinities by phage display.

21 January 2018

1 reference

Adoptive cell therapy for the treatment of patients with metastatic melanoma

21 January 2018

1 reference

Dendritic cells for active immunotherapy: optimizing design and manufacture in order to develop commercially and clinically viable products

21 January 2018

1 reference

Dendritic cell vaccines in melanoma: from promise to proof?

21 January 2018

1 reference

Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria

21 January 2018

1 reference

Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen.

21 January 2018

1 reference

Sequential immune escape and shifting of T cell responses in a long-term survivor of melanoma

21 January 2018

1 reference

A clinical development paradigm for cancer vaccines and related biologics

21 January 2018

1 reference

A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by gene MAGE-3.

21 January 2018

1 reference

Transfection of dendritic cells with in vitro-transcribed CMV RNA induces polyclonal CD8+- and CD4+-mediated CMV-specific T cell responses.

21 January 2018

1 reference

Delivery of tumor-derived RNA for the induction of cytotoxic T-lymphocytes

21 January 2018

1 reference

Quantitating protein synthesis, degradation, and endogenous antigen processing

21 January 2018

1 reference

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

21 January 2018

1 reference

Anchor sequence-dependent endogenous processing of human immunodeficiency virus 1 envelope glycoprotein gp160 for CD4+ T cell recognition

21 January 2018

1 reference

Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy

21 January 2018

1 reference

Endogenous MHC class II processing of a viral nuclear antigen after autophagy.

21 January 2018

1 reference

A role for intercellular antigen transfer in the recognition of EBV-transformed B cell lines by EBV nuclear antigen-specific CD4+ T cells.

21 January 2018

1 reference

Processing and presentation of HLA class I and II epitopes by dendritic cells after transfection with in vitro-transcribed MUC1 RNA.

21 January 2018

1 reference

Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens

21 January 2018

1 reference

Presentation of a cytosolic antigen by major histocompatibility complex class II molecules requires a long-lived form of the antigen

21 January 2018

1 reference

A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection.

21 January 2018

1 reference

Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E(2) regulates the migratory capacity of specific DC subsets

21 January 2018

1 reference

Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function

21 January 2018

1 reference

Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance

21 January 2018

1 reference

Efficient nonviral transfection of dendritic cells and their use for in vivo immunization

21 January 2018

1 reference

7 January 2021

1 reference

7 January 2021

Telomerase mRNA-transfected dendritic cells stimulate antigen-specific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer

1 reference

7 January 2021

mRNA-based electrotransfection of human dendritic cells and induction of cytotoxic T lymphocyte responses against the telomerase catalytic subunit (hTERT)

1 reference

7 January 2021

Clinical-grade manufacturing of autologous mature mRNA-electroporated dendritic cells and safety testing in acute myeloid leukemia patients in a phase I dose-escalation clinical trial

1 reference

7 January 2021

Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8+ cytotoxic-T-cell responses: evidence for immunoselection of antigen-loss variants in vivo

1 reference

7 January 2021

A novel autocrine pathway of tumor escape from immune recognition: melanoma cell lines produce a soluble protein that diminishes expression of the gene encoding the melanocyte lineage melan-A/MART-1 antigen through down-modulation of its promoter

1 reference

7 January 2021

Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions

1 reference

7 January 2021

Efficient chemokine-dependent migration and primary and secondary IL-12 secretion by human dendritic cells stimulated through Toll-like receptors

1 reference

7 January 2021