(Q45868497)

17 December 2017

title

Production of a severe cystic fibrosis mutation in mice by gene targeting (English)

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17 December 2017

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7

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author name string

Ratcliff R

1

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17 December 2017

Evans MJ

2

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17 December 2017

Cuthbert AW

3

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17 December 2017

MacVinish LJ

4

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17 December 2017

Foster D

5

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17 December 2017

Anderson JR

6

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17 December 2017

language of work or name

English

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publication date

1 May 1993

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17 December 2017

published in

Nature Genetics

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17 December 2017

volume

4

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17 December 2017

issue

1

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17 December 2017

page(s)

35-41

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17 December 2017

Nucleoside triphosphates are required to open the CFTR chloride channel.

cites work

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The spectrum of cystic fibrosis mutations

21 January 2018

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Cystic fibrosis in the mouse by targeted insertional mutagenesis

21 January 2018

1 reference

Ion transport characteristics of the murine trachea and caecum

21 January 2018

1 reference

Activation of chloride channels in normal and cystic fibrosis airway epithelial cells by multifunctional calcium/calmodulin-dependent protein kinase

21 January 2018

1 reference

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

21 January 2018

1 reference

Maturation and function of cystic fibrosis transmembrane conductance regulator variants bearing mutations in putative nucleotide-binding domains 1 and 2

21 January 2018

1 reference

Chloride channels and anion fluxes in a human colonic epithelium (HCA-7)

21 January 2018

1 reference

Defective regulation of outwardly rectifying Cl- channels by protein kinase A corrected by insertion of CFTR

21 January 2018

1 reference

A pgk::hprt fusion as a selectable marker for targeting of genes in mouse embryonic stem cells: disruption of the T-cell receptor δ-chain-encoding gene

21 January 2018

1 reference

Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter

21 January 2018

1 reference

A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice

21 January 2018

1 reference

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

21 January 2018

1 reference

7 January 2021

Identification of the cystic fibrosis gene: genetic analysis

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7 January 2021

Cystic fibrosis mouse with intestinal obstruction

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7 January 2021

An animal model for cystic fibrosis made by gene targeting

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7 January 2021

Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis

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7 January 2021

Quantitative assessment of exocrine pancreatic function in infants and children

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7 January 2021

A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung

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7 January 2021

Activation of an apical Cl- conductance by Ca2+ ionophores in cystic fibrosis airway epithelia

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7 January 2021

Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia

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7 January 2021

Antisense oligodeoxynucleotides to the cystic fibrosis transmembrane conductance regulator inhibit cAMP-activated but not calcium-activated chloride currents

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7 January 2021

Mislocalization of ΔF508 CFTR in cystic fibrosis sweat gland

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7 January 2021

Na+ transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation

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7 January 2021

Abnormal apical cell membrane in cystic fibrosis respiratory epithelium. An in vitro electrophysiologic analysis

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7 January 2021

Abnormal Ion Permeation Through Cystic Fibrosis Respiratory Epithelium

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7 January 2021

Cloning the mouse homolog of the human cystic fibrosis transmembrane conductance regulator gene.

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7 January 2021

Disruption of the cystic fibrosis transmembrane conductance regulator gene in embryonic stem cells by gene targeting.

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7 January 2021

Identifiers

DOI

10.1038/NG0593-35

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17 December 2017

Dimensions Publication ID

1014274397

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17 December 2017