(Q45869660)

17 December 2017

title

Improved safety through tamoxifen-regulated induction of cytotoxic genes delivered by Ad vectors for cancer gene therapy (English)

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17 December 2017

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Pützer BM

1

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17 December 2017

Stiewe T

series ordinal

2

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17 December 2017

Crespo F

series ordinal

3

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17 December 2017

Esche H

series ordinal

4

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17 December 2017

publication date

1 August 2000

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

7

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17 December 2017

issue

15

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17 December 2017

page(s)

1317-1325

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17 December 2017

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

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CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

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Endocrine pharmacology of antiestrogens as antitumor agents

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Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo

21 January 2018

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Combination therapy with interleukin-2 and wild-type p53 expressed by adenoviral vectors potentiates tumor regression in a murine model of breast cancer

21 January 2018

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Recombinant E1-deleted adenovirus-mediated gene therapy for cancer: efficacy studies with p53 tumor suppressor gene and liver histology in tumor xenograft models

21 January 2018

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Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

Interleukin 12 and B7-1 costimulatory molecule expressed by an adenovirus vector act synergistically to facilitate tumor regression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

Induction of S-phase entry by E2F transcription factors depends on their nuclear localization

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

Adenovirus-mediated regulable target gene expression in vivo

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax.

21 January 2018

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Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

Use of a membrane-localized green fluorescent protein allows simultaneous identification of transfected cells and cell cycle analysis by flow cytometry

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

Manipulation of adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

Electroporation in ‘intracellular’ buffer increases cell survival

21 January 2018

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p14ARF links the tumour suppressors RB and p53.

21 January 2018

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E1A is sufficient by itself to induce apoptosis independent of p53 and other adenoviral gene products.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

Deregulated c-myc expression in quiescent CHO cells induces target gene transcription and subsequent apoptotic phenotype

21 January 2018

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7 January 2021

Human adenovirus vectors for gene transfer into mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

7 January 2021

Apoptosis induction by E2F-1 via adenoviral-mediated gene transfer results in growth suppression of head and neck squamous cell carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

7 January 2021

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

7 January 2021

Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301235

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301235

1 reference

17 December 2017

Dimensions Publication ID

1007287641

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1 reference

17 December 2017