(Q45870768)

17 December 2017

title

Successful target cell transduction of capsid-engineered rAAV vectors requires clathrin-dependent endocytosis (English)

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17 December 2017

author name string

S Uhrig

1

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17 December 2017

O Coutelle

2

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17 December 2017

T Wiehe

3

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17 December 2017

L Perabo

4

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17 December 2017

M Hallek

5

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17 December 2017

H Büning

6

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17 December 2017

publication date

9 June 2011

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

19

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17 December 2017

issue

2

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17 December 2017

page(s)

210-218

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17 December 2017

Recent developments in adeno-associated virus vector technology

cites work

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors

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Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transfer

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Adeno-associated virus serotypes: vector toolkit for human gene therapy

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Identification of a heparin-binding motif on adeno-associated virus type 2 capsids

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Adeno-associated virus type 2 contains an integrin alpha5beta1 binding domain essential for viral cell entry

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Heparan sulfate proteoglycan binding properties of adeno-associated virus retargeting mutants and consequences for their in vivo tropism

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

RGD inclusion in VP3 provides adeno-associated virus type 2 (AAV2)-based vectors with a heparan sulfate-independent cell entry mechanism

21 January 2018

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21 January 2018

Virus entry: open sesame

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Internalization and trafficking of cell surface proteoglycans and proteoglycan-binding ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Clathrin- and caveolae-independent entry of feline infectious peritonitis virus in monocytes depends on dynamin

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Adeno-associated virus type 5 exploits two different entry pathways in human embryo fibroblasts

21 January 2018

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Deletion of penton RGD motifs affects the efficiency of both the internalization and the endosome escape of viral particles containing adenovirus serotype 5 or 35 fiber knobs

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Adeno-associated virus (AAV)-7 and -8 poorly transduce vascular endothelial cells and are sensitive to proteasomal degradation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradation

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.

21 January 2018

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A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin.

21 January 2018

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Targeting tumors with non-viral gene delivery systems.

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Targeted transduction via CD4 by a lentiviral vector uses a clathrin-mediated entry pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

A novel IRQ ligand-modified nano-carrier targeted to a unique pathway of caveolar endocytic pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Combined genetic and chemical capsid modifications enable flexible and efficient de- and retargeting of adenovirus vectors

21 January 2018

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https://api.crossref.org/works/10.1038%2FGT.2011.78

Rho GTPases and the control of cell behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

A conformational change in the adeno-associated virus type 2 capsid leads to the exposure of hidden VP1 N termini

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Intrinsic phospholipase A2 activity of adeno-associated virus is involved in endosomal escape of incoming particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Intracellular trafficking of adeno-associated viral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

The interaction between the fiber knob domain and the cellular attachment receptor determines the intracellular trafficking route of adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

In vitro selection of viral vectors with modified tropism: the adeno-associated virus display

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Standard heparin, low molecular weight heparin, low molecular weight heparinoid, and recombinant hirudin differ in their ability to inhibit transduction by recombinant adeno-associated virus type 2 vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Enhancement of gene transfer with recombinant adeno-associated virus (rAAV) vectors into primary B-cell chronic lymphocytic leukemia cells by CpG-oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Adeno-associated virus type 2 binds to a 150-kilodalton cell membrane glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

7 January 2021

Engineering adeno-associated virus serotype 2-based targeting vectors using a new insertion site-position 453-and single point mutations

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

7 January 2021

An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

7 January 2021

Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.78

7 January 2021

Identifiers

DOI

10.1038/GT.2011.78

1 reference

17 December 2017

Dimensions Publication ID

1034307911

0 references

1 reference

17 December 2017