(Q45871456)

English

Determinants of the factor IX mutational spectrum in haemophilia B: an analysis of missense mutations using a multi-domain molecular model of the activated protein

scientific article published in December 1994

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scholarly article

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

Determinants of the factor IX mutational spectrum in haemophilia B: an analysis of missense mutations using a multi-domain molecular model of the activated protein (English)

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

0 references

coagulation factor IX

0 references

0 references

David N. Cooper

4

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

author name string

A I Wacey

1

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

M Krawczak

2

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

V V Kakkar

3

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

publication date

1 December 1994

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

94

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

594-608

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

6

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

https://scigraph.springernature.com/pub.10.1007/bf00206951

0 references

Structural and energetic consequences of disruptive mutations in a protein core

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid replacements in yeast iso-1-cytochrome c. Comparison with the phylogenetic series and the tertiary structure of related cytochromes c.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of Ca2+ prothrombin fragment 1 including the conformation of the Gla domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The binding of human factor IX to endothelial cells is mediated by residues 3-11

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Active site and exosite binding of alpha-thrombin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of human des(1-45) factor Xa at 2.2 A resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A molecular model of the serine protease domain of activated protein C: application to the study of missense mutations causing protein C deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Codon usage tabulated from the GenBank genetic sequence data.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and characterization of human factor IX and factor IX-factor X chimeras in mouse C127 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function relationships of epidermal growth factor modules in vitamin K-dependent clotting factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construction, expression, and characterization of a chimera of factor IX and factor X. The role of the second epidermal growth factor domain and serine protease domain in factor Va binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational effects on protein stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gamma-carboxyglutamate-containing proteins and the vitamin K-dependent carboxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative modeling methods: application to the family of the mammalian serine proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct sequencing of the activation peptide and the catalytic domain of the factor IX gene in six species

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of protein stability and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Protein Data Bank: a computer-based archival file for macromolecular structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleotide sequence of the gene for human factor IX (antihemophilic factor B)

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular biology of hemophilia B

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mutational spectrum of single base-pair substitutions causing human genetic disease: patterns and predictions

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computer-generated models of blood coagulation factor Xa, factor IXa, and thrombin based upon structural homology with other serine proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The active site of membrane-bound meizothrombin. A fluorescence determination of its distance from the phospholipid surface and its conformational sensitivity to calcium and factor Va

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Missense mutations and evolutionary conservation of amino acids: evidence that many of the amino acids in factor IX function as "spacer" elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T296----M, a common mutation causing mild hemophilia B in the Amish and others: founder effect, variability in factor IX activity assays, and rapid carrier detection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the epidermal growth factor-1 and hydrophobic stack domains of human factor IX in binding to endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How different amino acid sequences determine similar protein structures: the structure and evolutionary dynamics of the globins

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A general method applicable to the search for similarities in the amino acid sequence of two proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the functional defect in factor IX Alabama. Evidence for a conformational change due to high affinity calcium binding in the first epidermal growth factor domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Domain structure and domain-domain interactions in human coagulation factor IX

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping of monoclonal antibodies to human factor IX

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1H NMR assignment and secondary structure of the Ca2(+)-free form of the amino-terminal epidermal growth factor like domain in coagulation factor X.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factor IX Fukuoka. Substitution of ASN92 by His in the second epidermal growth factor-like domain results in defective interaction with factors VIIa/X.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional nuclear magnetic resonance structures of mouse epidermal growth factor in acidic and physiological pH solutions

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haemophilia B: database of point mutations and short additions and deletions--fourth edition, 1993

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Missense mutations and the magnitude of functional deficit: the example of factor IX.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid difference formula to help explain protein evolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/7989034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00206951

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/7989034

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