(Q45873074)

17 December 2017

title

Overexpression of PAI-1 prevents the development of abdominal aortic aneurysm in mice (English)

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17 December 2017

abdominal aortic aneurysm

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1 reference

Qian HS

1

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17 December 2017

Gu JM

2

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17 December 2017

Liu P

3

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17 December 2017

Kauser K

4

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17 December 2017

Halks-Miller M

5

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17 December 2017

Vergona R

6

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17 December 2017

Sullivan ME

7

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17 December 2017

Dole WP

8

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17 December 2017

Deng GG

9

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17 December 2017

publication date

22 November 2007

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

15

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17 December 2017

issue

3

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17 December 2017

page(s)

224-232

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.gt.3303069

exact match

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cites work

Pathogenesis of abdominal aortic aneurysm: an update and look toward the future

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Angiotensin II increases urokinase-type plasminogen activator expression and induces aneurysm in the abdominal aorta of apolipoprotein E-deficient mice

21 January 2018

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Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease.

21 January 2018

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Atherosclerosis — An Inflammatory Disease

21 January 2018

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Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Antiatherosclerotic and antioxidative effects of captopril in apolipoprotein E-deficient mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

uPA, uPAR, PAI-1: key intersection of proteolytic, adhesive and chemotactic highways?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Reciprocal regulation of urokinase receptor (CD87)-mediated cell adhesion by plasminogen activator inhibitor-1 and protease nexin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

The influence of 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene promoter on the incidence, growth and operative risk of abdominal aortic aneurysm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Imaging transgene expression in live animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Optical imaging of in vivo gene expression: a critical assessment of the methodology and associated technologies.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Urokinase plasminogen activator receptor promotes macrophage infiltration into the vascular wall of ApoE deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Prevention of aneurysm development and rupture by local overexpression of plasminogen activator inhibitor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Plasminogen activator inhibitor type 1 increases neointima formation in balloon-injured rat carotid arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Plasminogen activator inhibitor-1 from bone marrow-derived cells suppresses neointimal formation after vascular injury in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Gene transfer of NAD(P)H oxidase inhibitor to the vascular adventitia attenuates medial smooth muscle hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Adventitial growth factor signalling and vascular remodelling: potential of perivascular gene transfer from the outside-in

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Plasminogen activators in abdominal aortic aneurysmal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Mouse models of abdominal aortic aneurysms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

Inflammation, metalloproteinases, and increased proteolysis: an emerging pathophysiological paradigm in aortic aneurysm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Urokinase-type plasminogen activator plays a critical role in angiotensin II-induced abdominal aortic aneurysm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Regulation of cell adhesion by PAI-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Association of the 4G/5G polymorphism in the promoter region of plasminogen activator inhibitor-1 with abdominal aortic aneurysms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Expression of fibrinolytic genes in atherosclerotic abdominal aortic aneurysm wall. A possible mechanism for aneurysm expansion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Plasminogen activator inhibitor 1 and vitronectin protect against stenosis in a murine carotid artery ligation model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Attenuation of neointima formation following arterial injury in PAI-1 deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Adventitial remodeling after coronary arterial injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Identification of a potential role for the adventitia in vascular lesion formation after balloon overstretch injury of porcine coronary arteries

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Vascular gene transfer : from bench to bedside

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Matrix metalloproteinase-8 and -9 are increased at the site of abdominal aortic aneurysm rupture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303069

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3303069

1 reference

17 December 2017

Dimensions Publication ID

0 references

1 reference

17 December 2017